[Question #10068] Sprayed with Medication
26 months ago
|
Dear Doctors Hook and Handsfield, Thank you for taking my question. So, I was finishing a medical procedure 2 days ago and anesthesia was trying to inject more Propofol (white-colored anesthetic). Unfortunately, the IV catheter was not taped properly and came out of the patient's vein and sprayed Propofol at least 4 feet away from where I was standing. I was turned to the side and was not aware this happened. I was wearing a mask, eye-glasses, and radiation goggles over my eye-glasses but they were somewhat slipped forward on my nose. I felt a drop hit my forehead but cannot rule out a speck/drop hitting my eye. I inspected the floor and end of the bed where I was standing and saw only white droplets and a puddle of Propofol but cannot be 100% sure there was no blood mixed in. The patient is low risk, I think, 55 yo married with 3 kids with a history of diabetes, coronary disease post stent placement 2 years ago but does have a history of bipolar manic (they can be hypersexual?) and depression. I went ahead and finished the case and washed my face/forehead and eyes with soap and water 5 minutes later. I considered at least asking more questions about the patient's HIV/Hepatitis status but the patient had already been discharged and a phone call later went to voicemail. I do see the patient back in 1 week. So 1)Would you pursue testing of the patient for HIV/Hepatitis based on this history and exposure? I don't want to offend them and I have been seeing this patient for 2 years ongoing basis for his chronic spine pain conditions. 2) Do you think I need to pursue PEP? 3) Should I test for HIV/HEP in 4 weeks (4th generation Ag/AB) test? My main concern is I cannot 100% rule out any speck of this fluid hitting my eye. Thanks for your expertise.
![]() |
Edward W. Hook M.D.
26 months ago
|
Welcome to our Forum. Thanks for your questions and your implied confidence in our service. I'll be glad to comment. I would have no concerns about the possibility of having acquired HIV or other blood borne infections from the events you describe. I say this based on a combination of factors which, when considered together make your changes of being infected virtually zero. These facts include: the patient (older and epidemiologically low risk), the fact that the sprayed Propofol came from the tubing going into the patient's vein, not from the vein itself), and the low probability that any of the spray entered your eye. Tp these facts I would add the fact that there are no instances in which sneezes or other sources of spray have NEVER be proven to transmit HIV.
I'm not sure in what country this event occurred but the likelihood that this person had untreated HIV is infinitesimal given his medical history which implies that he has received good medical care in the past.
Thus, in response to your specific questions:
1)Would you pursue testing of the patient for HIV/Hepatitis based on this history and exposure? I don't want to offend them and I have been seeing this patient for 2 years ongoing basis for his chronic spine pain conditions.
Whether or not to test him is up to you. If you chose to do so to address your concerns, you might just inform him that during the procedure there was some "spray" which occurred during the procedure and that, out of an abundance of caution, you'd like to test him for possible but unlikely infections including hepatitis and HIV. I would not consider such a request offensive if I were your patient.
2) Do you think I need to pursue PEP?
Absolutely not
3) Should I test for HIV/HEP in 4 weeks (4th generation Ag/AB) test?
I would not test if I were you. If you test him and he is negative, then again, there is no need for you to test as persons with negative tests would not be infectious to you.
I hope that this perspective is useful to you. EWH
---
26 months ago
|
Thanks for the response Dr. Hook. I am in the USA so the patient does have great care. I have a few follow up questions if you do not mind...you mentioned..".....there are no instances in which sneezes or other sources of spray have NEVER be proven to transmit HIV." Does this never case transmission include pure bloody fluid eye exposure in HIV positive patients? I was always told in that case it would be 1 in 1000 risk. In my case, I just cannot say how much blood, if any, was "mixed in" with the medication Propofol as the catheter was in the patient vein. Also, I am not sure how much "eye protection" I had as both my lead glasses and prescription glasses underneath had slid forward onto the front of my nose. I did get some eye irritation after procedure but not sure if it was the Propofol exposure or when I washed my face/eyes with soap. Would your advice change any if playing devils advocate it was full bloody exposure and no eye protection with spray into eyes, in worst case scenario? Patient does have history of bipolar manic/depressive which can be hypersexual. Thanks for your input.
![]() |
Edward W. Hook M.D.
26 months ago
|
How sad to see a trained health care professional go down the "but what if..." rabbit hole. It serves no purpose and I will not play those games. I know of no instances where, in a health care setting, a clinician has acquired HIV from the sort of exposure you describe. I outlined the reasoning which supports this observation. You know very well that you were not sprayed with "pure bloody fluid". Further, while I didn't mention it in my initial comments, please also remember that the blink reflex, the fastest reflex in the human body, protects against such exposures over and above the eye protection that you are now questioning.
Your eye irritation was likely due to your attempts to wash out your eyes.
FYI most persons with mental illness do not have HIV. If you are all that concerned, get the patient tested. My advice however is to move on and put your concerns behind you. EWH
---
25 months ago
|
Hey Dr. Hook. I ended up testing the patient and patient was negative for HEP/HIV. Also, I did not intend to "go down the what if hole" but was curious how they got to the 1:1000 risk of HIV transmission with mucous membrane exposure? Any studies you can point me to? Anyways, thanks for all you do and appreciate your expertise.
![]() |
Edward W. Hook M.D.
25 months ago
|
Thanks for your follow-up. I'm pleased but not surprised at the results you describe and hope that these results are comforting to you.
The figure of less than 1 infection per 1000 sexual exposures is based on numerous careful studies and is reflected on the information available on the CDC website which admittedly is not easy to navigate. That is a good place to start. FYI, based on your reply and concerns expressed by you and multiple other Forum users, I have suggested that the CDC create its own FAQ portal.
This completes this thread which will soon be closed.
EWH
---