[Question #10094] HIV Symptoms and Risk

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25 months ago
Dear Dr. Handsfield,

I made a very big mistake while intoxicated, and had unprotected insertive vaginal sex with 2 different CSWs in Dubai.  

On the 9th night after the incident, while sleeping, I had some mild stomach pain which I attributed to dinner.  The next morning,  I had back pain in the mid/upper back region which started a few hours after I woke up.  My back felt stiff and hurt mainly when I moved and did not hurt when I was lying down.  I took some paracetamol but it did not help much.  I did measure my temperature and there was no fever (but it was after the paracetamol).  I had not done anything to aggravate my back and have never had pain like this before.  By the next morning, I would say it was 95% improved and otherwise feel fine.  I know the risk is high.  And the timeline for ARS is in the range.  My questions are:

1.    Is this back pain what medical professionals would refer to as myalgia or arthralgia which is a common symptom of ARS? 

2.    Is myalgia/arthralgia associated with ARS or viral infections like the flu characterized by stiffness and pain on movement or pain regardless of movement?

3.    Can one have viral related myalgia/arthralgia without fever?

4.    Can ARS present as back pain like this for 1-2 days without any other symptom like sore throat, fever, rash, etc.?  Or maybe the other symptoms were too mild for me to have noticed?

5.    I can’t take the test here in Dubai because it is reportable and they deport you if its positive.  So I plan to test in a different country in 10 days.   Would the Duo test be sufficient (it would be 20 days post exposure by then and 10 days post symptom onset) or should I do the RNA test?

Thanks for your insight

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Edward W. Hook M.D.
25 months ago
Welcome to the Forum.  Dr. Handsfield and I share the Forum and I will be answering your question today.  The encounters you describe were risky but not necessarily high risk.  Most CSWs in Dubai do not have HIV (or other STIs) and even when they do, most exposures (fewer than 1 in 1,000) result in infection.   Nonetheless, I understand your concerns.  As I'll explain below, the symptoms you describe do not suggest the ARS of recently acquired HIV.  Persons with the ARS have high fevers (admittedly yours may have been modified by your paracetamol), muscle aches (this may have been your back ache), and severe sore throat.   Typically these symptoms begin a1-3 weeks after an exposure and last for several days or a week. Even when persons have this "classical" collection  of ARS-type symptoms, fewer than 1% turn out to have HIV, the remainder having other far more common viral flu-like illnesses including influenza, COVID-19, and other viruses which are not typically tested for.  If your symptoms were due to HIV, an HIV blood tests would be positive at this time- symptoms are always accompanied by positive tests.  In answer to your specific questions:

1.    Is this back pain what medical professionals would refer to as myalgia or arthralgia which is a common symptom of ARS? 
It could be.  See above

2.    Is myalgia/arthralgia associated with ARS or viral infections like the flu characterized by stiffness and pain on movement or pain regardless of movement?
Most often the person feels poorly but the discomfort is primarily associated with movement.

3.    Can one have viral related myalgia/arthralgia without fever?
Not the ARS

4.    Can ARS present as back pain like this for 1-2 days without any other symptom like sore throat, fever, rash, etc.?  Or maybe the other symptoms were too mild for me to have noticed?
No, this would not be the ARS but some other process

5.    I can’t take the test here in Dubai because it is reportable and they deport you if its positive.  So I plan to test in a different country in 10 days.   Would the Duo test be sufficient (it would be 20 days post exposure by then and 10 days post symptom onset) or should I do the RNA test?
You do not need an RNA test to evaluate your symptoms, a standard DUO will suffice.  I anticipate that when you test, you will find that you do not have HIV.

I hope this information is helpful.  EWG
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25 months ago
Dear Dr. Hook,

As an update, later in the day I developed a mild sore throat throughout the day, and the back pain was still present though diminished. In the evening I developed a persistent headache and when I went to sleep, my skin felt hot/burning, but when I checked my temperature there was no fever. I had a very disturbed sleep with vivid dreams and took a paracetamol at 2:30am. When I woke there was no fever, muscle pain, sore throat, headache. So it seems symptoms lasted Thursday night to Sunday morning.

1. Can you please explain why you feel the muscle pain I had cannot be HIV related unless there is fever?
2. Does ARS always have HIGH fever, SEVERE sore throat, and muscle pain?
3. Does the updated info - ie sore throat, headache, etc. change your view that this is not ARS or HIV related?

Thanks
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Edward W. Hook M.D.
25 months ago
You ask questions about the ARS. The ARS is uncommon but well defined. The ARS is comprised of a severe sore throat, severe muscle aches, and high fevers, sometimes accompanied by diarrhea or a generalized skin rash. all occurring at the same time and last at least several days. The time sequence of your events really does not suggest the ARS following your relatively low risk exposure. If you feel that I am incorrect, you should test. As I said above, if you test your symptoms were due to the ARS your test would be positive.  I am confident they will not be. 

1.  See above.  We have DEFINITIONS for a reason.
2.  Yes
3.  No

EWH 
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25 months ago
1. Sorry, I just wanted to know if there is any medical reason as to why muscle pain can't present as a symptom of acute HIV in the absence of fever?
2. If ARS is uncommon, does that mean it is common to have symptoms not typical of ARS during acute HIV or no symptoms at all?
3. If you were me, would you feel the need to test based on the risk, exposure, and symptoms?

Thanks
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Edward W. Hook M.D.
25 months ago
As you know, we provide up to three responses to each client's questions.  This will be my 3rd and final response, following which the thread will be closed.  After that you should not need to return to the Forum.  Should you return with further repetitive, anxiety driven questions, your thread my be closed without a response and without return of your posting fee.  On to your follow-up questions:

1. Sorry, I just wanted to know if there is any medical reason as to why muscle pain can't present as a symptom of acute HIV in the absence of fever?
Syndromes are described and defined to assist clinicians interpret their patients' findings and to guide diagnostic evaluations.  The ARS as described above is used to identify persons whose symptoms may benefit from evaluation for recently acquired HIV.  Any symptoms whether that is muscle pain or discomfort in the big toe of the foot could occur in someone who had recently acquired HIV  but it would not be a SYNDROME.  The symptoms you have described are not the ARS.  The exposures you describe are statistically relatively low risk- given the relatively low rate of HIV among CSWs in Dubai (certainly less than 5%, probably less than 1%) and the low risk of acquiring HIV from any single exposure to an untreated, HIV infected person (on average less than 1 infection/1000 encounters) your statistical risk is less than  1 in 5000 (i.e. chances are less than 99.8% that you acquired HIV) from you two unprotected exposures and probably far lower.  You need to move on.  You are having trouble doing that.  The solution to this problem is not more "what if..." questions but to get tested

2. If ARS is uncommon, does that mean it is common to have symptoms not typical of ARS during acute HIV or no symptoms at all?
Many persons who acquire HIV do not recall the ARS or other symptoms which are statistically associated with the infection.

3. If you were me, would you feel the need to test based on the risk, exposure, and symptoms?
If I were you I would not be particularly worried but I might test at 6 weeks following my exposure out of an abundance of caution.

End of thread .  EWH
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