[Question #10291] Question about LGV
24 months ago
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Hello I have a question about lymphogranuloma venereum. I am a heterosexual man. I have tested for chlamydia via urogenital and a throat swab by quest rna. I have had a small lymph node in my neck but after getting it scanned doctors said it wasn’t a big deal. But I noticed there is a blood test for Lgv. Do I need a Lgv blood test as well to rule it out? Or is my chlamydia/gonnorhea urogenital and throat swabs from quest conclusive that I do not have lymphogranuloma venereum? Is there any other test I need? I have been worried sick about this
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H. Hunter Handsfield, MD
24 months ago
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Welcome to the forum. Thank you for your confidence in our services.
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You needn't concerned about LGV; you don't have it. It is not a likely cause of a single small lymph node, especially in the neck. Equally important, the current dramatic rise in LGV cases (for the past 10-15 years) has been entirely in men having sex with other men, and in them it is limited almost entirely to rectal infection. There have been a few reports of single cases of oral/pharyngeal LGV, but the very fact of individual cases being reported in the medical literature reflects how rare it is. (Single case reports almost always have the main goal of alerting clinicians to rare and therefore easily missed conditions.) And LGV is not a subtle infection and almost by definition, never asymptomatic. Finally, the standard swab tests detect the LGV strains of chlamydia just as well as they diagnose standard, non-LGV types. So your negative test results prove you didn't have LGV when you were tested.
For all these reasons, you can be sure you do not have it; thThe LGV antibody test is diagnostically useless -- it misses most LGV infections and remains negative in many.
Don't worry at all about this!
I hope these comments are helpful. Let me know if anything isn't clear.
HHH, MD
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24 months ago
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Thank you for your reply. Also I forgot to mention that my test for urogenital was a urine test for gonnorhea/chlamydia would that cover it? Also I have heard that tests are done by swabbing a lymph node? Do I need that? Hypothetically if I did have Lgv in my neck nodes would a regular quest chlamydia trachomatis/gonnorhea rna tma throat swab be able to find it? Also I got the test done 3 months after the last sexual exposure. Would it be conclusive?
24 months ago
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Also I forgot to mention. I’ve also been tested for hepatitis c,a,b, syphilis, HIV 4th gen, trichomoniasis and even mycoplasma genitalium. I’ve only received throat swabs for chlamydia and gonnorhea though. Are those the only throat swabs you recommend getting? Do I need testing for anything else? I just want to get on with my life already. I have symptoms besides a small lymph node and minor redness in my throat. But my ent said I’m fine. I apologize for the double post.
24 months ago
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Whoops sorry I meant to say I have NO symptoms besides the small lymph node and minor redness but my ent said I’m fine
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H. Hunter Handsfield, MD
24 months ago
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Testing for gonorrhea almost always automatically includes a chlamydia test as well. Double check with your lab, or the lab report, or your doctor to be certain.
Yes, chlamydia and gonorrhea are the only STI tests routinely done in the throat. No others are needed: I explained why above.
Why do you doubt your ENT's advice? I agree! The lymph node never was a legitimate concern for LGV or any other STD.
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24 months ago
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Okay so a quest chlamydia/gonnorhea swab quest rna tma is good enough to detect Lgv?
24 months ago
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And yes my quest test included chlamydia trachomatis and neiserria gonnorhoeae rna tma at the same time
24 months ago
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Also forgot to mention. How long would someone have to wait after sexual encounter before getting a chlamydia/gonnorhea throat swab to be able to be detectable?
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H. Hunter Handsfield, MD
24 months ago
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The gonorrhea/chlamydia tests are conclusive within 4-5 days of exposure (probably 2-3 days, but 4-5 days is safest). And yes, the LGV strains of chlamydia show up on all standard chlamydia tests. It is not necessary to request an LGV test per se: negative routine chlamydia means LGV is absent. (At Quest and any other standard laboratory.)
That concludes this thread. I hope the discussion has been helpful. Best wishes and stay safe.
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