[Question #10384] Hiv anxiety

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23 months ago
I am a male and I had unprotected oral sex 3 times and protected vaginal sex 3 time with a Thailand CSW on May, 2023. After that I have sight tonsillitis 3 day later, however, tonsillitis becomes severe on day 10. Then I go to clinic and get ass needle and I recovered. I am afraid of hiv from that day and I can't move on. I have ag/ab test on 66 days, 82days, 95 days and 121 days and hiv1 rna test on 95 days, all are negative.
I have long foreskin and I didn't have circumcision surgery.
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23 months ago
I also have sore throat on 90 days(this is why I did rt-pcr test). Do I need to do the test again on six months? Thank you very much!
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H. Hunter Handsfield, MD
23 months ago
Welcome. Thank you for your confidence in our services.

You really needn't worry; for certain you do not have HIV. I understand how worrisome your symptoms may be, but several factors indicate HIV really should no longer be a concern for you. The exposure was very low risk, since the vaginal sex was condom protected and there has never been a known case of HIV transmitted by oral sex (oral to penis). Your sore throat was not HIV, which cannot cause symptoms of any kind sooner than 8-10 days after catching it; almost certainly you just caught a cold, which might have gone on to strep throat, which may explain why the injection (probably penicillin) was helpful. But most important, your test results are conclusive:  they prove for sure you do not have HIV. The AgAb tests are conclusive any time more than 6 weeks after exposure, and the RNA test conclusive after about two weeks. You have been really over tested -- don't have an. more tests, at 6 months or any other time.

And by the way, your circumcision status makes no difference:  although it slightly raises the risk of HIV if exposed, the test results overrule everything else. No matter how high the risk of HIV at the time, and no matter what symptoms there are, the test results tell the truth! Please don't worry any longer.

I hope these comments are helpful. Let me know if anything isn't clear.

HHH, MD

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23 months ago
REALLY thanks for your reply. They are really helpful. I have the following questions below.
1. If the symptoms are due to hiv, the ag/ab test will be positive few days later, and NAT test should be larger than 20 copies/ml immediately, is it right?
2. When I pulled the penis out of her vagina, the condom slid about halfway, but I felt that the condom still covered the foreskin. Can it be considered that condoms work?
3. My ag/ab test are smaller than 0.1 in korea clinic, but when I came back China, the result are 0.2. And doctors in China said that if larger than 0.5, it will be dangerous. Does is correct?
Thanks for picking my questions!
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H. Hunter Handsfield, MD
23 months ago
1. The AgAb test will be positive at the same time symptoms begin, or even before. And NAAT also would usually be positive (>20 copies) whenever there are symptoms.

2. It is common for the penis to withdraw from a condom that remains in the vagina. Protection against HIV and other STDs is considered complete when it happens.

3. With almost all laboratory based HIV blood tests, any value below the negative-positive cut-off value is equally negative. The same specimen tested 10 times would give 10 different numbers. As long as the number is below the cut-off, the result is equally negative. (I am unaware of any tests whose cut-off is as low as 0.5; for all tests in the US and Western Europe it's 0.9 to 1.1 But perhaps there is a test in your country with cut-off of 0.5.)
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23 months ago
I'm sorry that my statement misled you, in China, the cut off value is also 0.9~1.0. Some Chinese doctors said that if the the value is larger than 0.5, the probability of false negative is high, is this correct? 
In addition, I decide to take some anti-anxiety medicine if I still can't move on. Does the anti-anxiety medicine such as Mirtazapine affect the accuracy of hiv test?
They are my final questions. Thanks for you help!
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H. Hunter Handsfield, MD
23 months ago
I disagree about ELISA values >0.5 as likely false positive. I've never heard such a thing -- but perhaps your doctors know more about tests in use in China.

There are no medications or medical conditions of any kind that have any effect on HIV test reliability. That was once the case with the earliest antibody tests, not used for many years.

It is 100% certain you do not have HIV. Do not overthink it and do not search the web any further, and for sure do not have any more HIV tests!

That completes the two follow-up exchanges included with each question and so ends this thread. I hope the discussion has been useful. Best wishes and stay safe.
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