[Question #10484] Epstein-Barr Virus

22 months ago

I have experienced a wide range of symptoms in the past 4-5 months post a risky sexual encounter. I have tested negative for everything except for Epstein-Barr. I have just received my test results and have questions. My results are as follows:

EBV Ab VCA, igm- 38.9 (equivocal result)

EBV Ab VCA, igG- 31.8 (positive result)

EBV Nuclear Antigen Ab, igG- 183 (well above the 21.9 or greater positive marker)

How can I interpret these results?

How can I find out if I’m like the 90% of people who would test positive? Or if I’m a rare case of Chronic EBV (which I understand is very serious)?

I still plan on seeing a doctor in person but if there’s any info you can share I’d greatly appreciate it.

Edward W. Hook M.D.

22 months ago

Welcome to the Forum. Thanks for your questions. On this occasion I happened to pick up your question. In preparing to reply I reviewed your earlier interactions with Dr. Handsfield and agree with all that he said. The symptoms that you describe are consistent with any number of "every day" community acquired viral illnesses which are self-limited although they may take a while to resolve.

Your tests indicate that you, like the majority of the population have had EBV. The test results are consistent with your having had EBV at some time in the past. The numerical value of the tests, including the EBNA antibody, have no relationship to the timing or the severity of a past EB infection. There is virtually no chance that you have chronic EBV.

I'm also not sure why you even bothered to get tested for EBV. If you wish to seek the input of a physician, I would suggest you do so with an Infectious Diseases specialist. Few generalists will be familiar with these tests. EWH

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22 months ago

Thank you so much for your response. I brought the question or having the test done and my doctor was onboard. I have had a white tongue and other weird symptoms for months off and on and can’t get a answer as to why from two primary care doctors, two ENTs, and one dentist. I’m going to see an infectious disease specialist soon. I have one follow up question; regarding chronic ebv can you explain why it would be virtually impossible? My doctor said she’d have to refer me to the infectious disease specialist to ask that question. Thank you!

Edward W. Hook M.D.

22 months ago

Chronic EBV infection is a serious disease in which patients are for Aylor than yours. In addition, your laboratory tests do not support the diagnosis. I agree with your plans to see an infectious disease specialist. EWH.---

Edward W. Hook M.D.

22 months ago

Sorry my dictation lead to a typographical error. The first sentence should have” chronic EBV infection is a serious disease in which patients are for sicker than what you report.” EWH---

22 months ago

Thank you sir!