[Question #10639] Ureaplasma Resistance
21 months ago
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Starting Nov 26 I have taken 7 day doxy 2 pills once a day (forgot to take the very last pill so 6.5 days) and then after three days of nothing took 1g of Azithromycin followed by 3 days of 500 mg. Now I'm on 7 days of doxy again. I still feel a dull burning sensation in urethra after everything. How do I know if it has resistance to these meds? Was the 3 days between the doxy and azi too much to ruin treatment? And what tests can I take to test resistance? Should I take anything else instead given I still feel symptoms? When should I take a test again to see if I'm clear?
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H. Hunter Handsfield, MD
21 months ago
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Welcome to the forum. Thank you for your confidence in our services.
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I'd like to help, but this is an incomplete question; my advice will be much more useful with more information. Did you perhaps have a previous forum thread under a different username? If so, please identify it so I can see what advice you have had already. If not, what diagnosis was made before November 26 (almost a year ago)? (Or do you maybe mean October 26?) Nongonococcal urethritis? Cervicitis? Are you male or female? What was the nature of your sexual exposures or risks? What symptoms did you have to start? What lab tests were done and what were the results?
I'm looking forward to helping you when I understand your situation.
HHH, MD
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21 months ago
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Hello, sorry the test was done on October 26 a few weeks ago. The sexual exposure was oral, anal and vaginal, I am a male. I had no symptoms and a few days after exposure I just had a dull pain/burn in urethra. I got tested for Ghonorrea, Chlamydia, Trich and ureaplasma, the ureaplasma is what i tested postive for, everything else was negative
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H. Hunter Handsfield, MD
21 months ago
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Thanks for the additional information.
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No STD is a likely cause of "dull pain/burn" in the urethra. The main symptom of urethritis -- i.e. urethral infection due to gonorrhea, chlamydia, and nongonococcal urethritis (NGU) -- is discharge, often but not always with painful or uncomfortable urination. But discomfort alone doesn't suggest STD. Ureaplasma is entirely normal in the genital tract; it really should not be included in STD test panels. It causes no harm, no symptoms, and doesn't need treatment. But for what it's worth, doxycycline is active against ureaplasma; that your symptoms haven't improved is further evidence ureaplasma isn't the cause. Your test results show you have no infection that would be successfully treated by doxy. You do not need re-testing for ureaplasma or anything else.
If your symptoms continue and/or you remain concerned, keep working with your doctor. Good luck.
HHH, MD
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