[Question #10771] Infection Potential

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19 months ago
Hi.  A couple of weeks ago, I performed fellatio on someone that lasted two or three minutes max.  There was no ejaculation.  Several days ago, I began to develop an intense sore throat (a few days after being at a party that had some attendees with colds and/or flu).  I still have the sore throat with some possibly mild cold symptoms.  Within hours of the fellatio, I took a dosage of doxycilin (200 mg) and azithromycin (2mg) — and felt sick to the stomach the next day.  What are the chances I picked up an STI such as gonorrhea?  If I did acquire an STI, what are the chances I could pass it along by performing cunnilingus?  
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Edward W. Hook M.D.
19 months ago
Welcome to the Forum. Thanks for your questions.  I'll be glad to comment and suspect that you do not have oral gonorrhea but the best way to be sure is with a throat swab for gonorrhea (most throat cultures performed do not look for gonorrhea unless the clinician taking the swab is aware that this is a concern and specifically orders a test for gonorrhea)  Below I have listed the reasons I suspect your symptoms are not due to gonorrhea or some other STI:

1.  Most people are not infected and even when partners are infected, most single exposures do not result in infection.
2. Gonorrhea of the throat (the most common STI occurring following performing fellatio on an at risk partner) is typically asymptomatic.
3.  STIs are easier to prevent ant the doxycycline and azithromycin you took (I believe you got the dosages you reported wrong).  While these drugs are not specifically recommended for gonorrhea treatment, if taken, they are likely to prevent infection.

Regarding transmission IF you have oral gonorrhea, once again, cunnilingus is not an "efficient mechanism for gonorrhea transmission although it does occur rarely (there are no specific percentages to mention but is is uncommon for cunnilingus to result in gonorrhea transmission)

Bottom line- I doubt that you have gonorrhea or any other STI but, as I said above, if you want to be sure, you should be tested.  EWH
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19 months ago
Thanks for the quick response.  I did misstate the dosage of the azithromycin.  It was 2g (not 2 mg).   The doxycycline was 200mg (which I understand to be effective as post-exposure if taken with 24 hours).  If the risk cannot be quantified, is it safe to say I am in the very low risk category?  
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Edward W. Hook M.D.
19 months ago
Yes. a;; things considered the risk is close to zero.  EWH---
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19 months ago
Thanks again for your time and responsiveness.  As it turns out, I tested positive for Covid (despite vaccination) — hence the symptoms described).  For future reference, my oral sex experiences will be limited to cunnilingus which I perceive to be the most de minimis risk for an STI.  Final question — do you endorse the post-exposure administration of 200 mg of doxy within 24 hours (with or without azithromycin)?
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Edward W. Hook M.D.
19 months ago
Doxycycline post exposure prophylaxis (PEP) is highly effective for prevention of chlamydia and syphilis and somewhat protective in prevention of gonorrhea. It is recommended for persons at high risk for acquisition of STI‘s based on having had STI‘s of any sort in the past year and I agree with that recommendation. In your case, oral exposures are relatively lower risk for acquisition and transmission of these STI‘s then penile-vaginal or ano-genital sexual contact. The decision to use Doxy pep is always a personal decision. 

Addition of azithromycin to doxycycline for PEP adds little other than cost and the potential for side effects. Should you choose to use Doxy PEP, my recommendation would be to not bother with the azithromycin, which has not been studied. 

I hope this information is helpful to you. 

As you know, this third response completes this thread. Take care. EWH.
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