[Question #1140] regarding question 1132

48 months ago
Hello again I recently had a question that was answered but now I have some more issues once.

How accurate is the 4th generation test at 8.5 weeks?

I have developed headaches swollen lymph nodes still have diahreia and now I have a dry mouth and body aches is this possible seroconversion at 10 weeks?

I also forgot to mention that occasionally my gums do bleed does this affect my chance of being infected more on the giving of cunnilingus more?


Edward W. Hook M.D.
Edward W. Hook M.D.
48 months ago

Welcome back to our Forum.  As you probably know, Dr. Handsfield and I answer questions interchangeably and I happened to pick up your question today.  I reviewed your earlier interaction with Dr. Handsfield as well, the exposures you describe were, for all practical purposes, no risk.  Currently available tests for HIV are among the most reliable tests in all of medicine.  At any time more than 28 days (4 weeks) following an exposure, results of 4th generation tests are completely reliable and would not miss infection. In your case, you have now had two tests beyond that time and therefore can be doubly confident that you did not get HIV from the exposure you described. 

Headaches, swollen lymph nodes and diarrhea are all non-specific findings and your negative HIV tests completely rule out the possibility that they are somehow related to an HIV infection acquired over two months ago.  What you describe is a "flu-like illness" of the sort that is common year round, even in the summer.  I suspect that this is what is going on, perhaps amplified by your anxiety over your exposure. 

Bleeding gums has no effect on HIV risk during the performance of oral sex.  Nothing to worry about there. 

I hope my comments are helpful.  Thanks for your question, stay safe.  EWH

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48 months ago
Thank you Dr hook but I'm confused and don't understand the 4th generation test about antigen and antibodies and I am stressed and honestly idk what do I can't stop thinking about it and surfing the Web.
Edward W. Hook M.D.
Edward W. Hook M.D.
48 months ago

Perhaps you do not need to understand the chemistry, you asked for information and got it.  Don't mean to sound condescending but this is our business, that is the reason you came to us for information.

Briefly, 4th generation tests detect both antigen (the proteins of the virus) and antibodies that are created in response to infection.  since the virus is present before the antibodies are produced, 4th generation tests detect first virus, and then antibodies to the virus, resulting in results sooner than earlier tests which only tested for antibodies. 

Web surfing will only confuse and mislead you.  I urge you to contain your anxieties (guilt and shame-drive I suspect) and move forward.  EWH

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48 months ago
It's just really hard especially after I came down with these symptoms in all reality what are my statistics considering the act that was done and my testing etc.
Edward W. Hook M.D.
Edward W. Hook M.D.
48 months ago
Repeating your question does not change the answer.  You do not have HIV!!!!  You had a sexual exposure that has left you anxious and feeling guilty and coincidentally, more than two months later, you got the sort of viral illness that most people get from time to time.  Believe your tests.  EWH
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