[Question #11715] GW monogamous (i think) relationship
12 months ago
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Hello, I am in a ten year monogamous relationship. I am male and in my early 40s, my partner is female in her early 30s. I was recently diagnosed with genital warts, a second doctor diagnosed me with herpes but I think this may have been incorrect. I live in a developing nation and the second doctor didn't speak much English at all, i think she looked at the GW removal wounds and didn't understand that I had had electrocautery, so thought it was herpes, but I can't be sure. I then took an LLG herpes test which came back negative (i did this off my own back, the doctor told me i don't need it because she can diagnose herpes by sight).
I would like to know how possible it is that I developed genital warts after ten years in a monogamous relationship, without my girlfriend having cheated on me. And if I do have herpes, how likely am I to develop both genital warts and herpes simultaneously without infidelity having occurred?
A little further information, since 2017 I have been taking low dose methotrexate to control eczema. At the time the second doctor diagnosed me with herpes I had also developed flu like symptoms, as did many of my friends, so I'm not sure if that was herpes or something else that was going around.
I've been very concerned about all of this so sorry if this is a bit of a ramble and thanks for your help.
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H. Hunter Handsfield, MD
12 months ago
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Welcome to the forum. I'm happy to help.
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Your situation is not rare at all; we get such questions fairly commonly -- appearance of an HPV problem in a monogamous couple. The most common situation concerns an abnormal Pap smear in the female partner, but questions about warts are common as well. (I'm going to assume you are correct about the second doctor mis-diagnosing herpes. Genital warts treatment certainly could cause open skin lesions that could appear similar to herpes.)
Many HPV infections, perhaps all of them, are lifelong in that HPV DNA can persist in tissues for long periods, often for life. As a result, the virus can reactivate and cause warts, abnormal Pap smears, etc -- sometimes years after acquiring the virus. Therefore diagnosis of HPV problems often does not suggest either partner has acquired the virus recently and cannot be considered evidence of sexual infidelity. Undoubtedly that is the situation here. If you have not had other sex partners during your marriage, and if you have no other reason to suspect your wife has done so, I'm sure you can trust her.
At this point, the important thing is to complete treatment of your warts. Your wife also should be on the alert for developing warts herself -- undoubtedly she has been exposed to your HPV infection. She also should follow standard guidelines for period Pap smears, as should all adult women. However, she might have been exposed for many years to your HPV infection and is now immune to it; most likely she won't develop warts and Pap smears will be normal.
I hope this information is helpful. Let me know if anything isn't clear.
HHH, MD
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H. Hunter Handsfield, MD
12 months ago
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I forgot to respond to your comments about methotrexate and herpes. Methotrexate is immunosuppressive, but in the low doses used for eczema and other inflammatory conditions, it has little effect on susceptibility to infections. Probably it had nothing to do with the flu-like symptoms you had. With other personal contacts having similar symptoms, probably you had some other viral infection (cold, influenza, covid, etc) and had nothing to do with either herpes or the methotrexate.---
12 months ago
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Thanks for your reply, it's good to have reliable information, both doctors I saw told me it was impossible for me to develop the warts without my wife having cheated. We have been going through a rough couple of years and I do have some suspicion about what she's been up to, but I guess there's nothing that can be done about that. If it's OK, I have one more question. I had 4 small warts, all of which were removed by electrocautery 3 weeks ago, but one of them seems to be reappearing through the wound. Should I immediately go to have this removed again? I think I also have a new wart appearing. Also, around the time I saw the warts a small black dot appeared on my penis, the first doctor I saw told me it was almost certainly nothing to worry about, but I should photograph it every few months to see if it increases in size. Does this sound right to you? Thanks again
12 months ago
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Hello, I was just wondering if you'd missed my follow up question?
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H. Hunter Handsfield, MD
12 months ago
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Sorry for the delayed reply. Also sorry that you found two doctors who don't understand HPV infections! In any case, if indeed your wife has had other partners, there would be a possibility your warts are from a newly acquired HPV infection. It also is reasonable for the sex partners of anyone with genital warts to be examined themselves. On that basis, you should make sure your wife knows about your warts and that she should see her gyn for evaluation. You don't necessarily need to discuss any suspicion about her having other partners: it is routine for all partners of persons with genital warts to be evaluated, regardless of the sexual circumstances. (That said, perhaps it would be a good idea to have a frank discussion with her about all this. But this is a relationship issue, not one of STD management.
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All wart treatments are imperfect. You should return to the doctor or clinic where you were treated. Repeating the electrocautery might be necessary; or s/he might prescribe an additional treatment like imiquimod (Aldara) or other treatment.
12 months ago
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Thanks so much for your help, it's greatly appreciated
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H. Hunter Handsfield, MD
12 months ago
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Thanks for the thanks. I'm glad to have helped. Best wishes and stay safe.---