Welcome to the Forum. Thanks for your questions. I'll be glad to comment.  Hydrosalpinx is the medical term describing a fluid filled area of the fallopian tube, the tube that goes from the ovary to the uterus.  Hydrosalpinx occurs when the fallopian tube becomes blocked, most often due to scarring.  Scarring to cause hydrosalpinx has many possible causes including infections (STIs and other infections), scarring due to previous surgery or problems such as appendicitis, or endometriosis.  When hydrosalpinx occurs, it typically occurs long after an infection or other source of inflammation has occurred.  My sense is, that without knowing what is causing the problem, her doctor is treating both her and you with a number of antibiotics which would be effective against STIs as well as many other kinds of infection.  At this point there is probably no easy way to determine the cause of her hydrosalpinx.  You negative tests for STIs mentioned above suggest that your participation in cunnilingus and analingus two years ago is unlikely to be the cause   EWH---

Thanks for the additional information.  The internet is not your friend here.  As I mentioned above, there are many other things that can cause hydrosalpinx and there is no evidence that you’ve had an STI, much less infected your wife.  You’ll probably never know what has caused this problem but there’s no evidence it’s your fault.  Best to just move forward.  EWH---