October 2023 - had unprotected risky with another male. Got on PEP within 48 hours. 

November 2023- had sex with a woman while I was still taking pep. 

December 2023- finished PEP and tested negative 

January 2025- still testing negative

1. Could I have had hiv in my system that transmitted to my female partner while I was taking pep? 

2. Could I have infected her even though all of my tests are still negative? 

3. I was still been having unprotected sex with my female partner throughout 2024. If she was infected from our encounter in 2023, isn’t it likely that I would be positive for hiv? 

Yes it is.

Bottom line.  You were not infected in the Nov 2023 encounter that you describe.  Your were not infected and you could not have infected your female partner.  You are completely in the clear and there is no need for further testing related to this encounter.  

I hope this information is helpful.  EWH

1. Is it possible that some of the virus integrated in my DNA, infected my partner, then was killed in my system from the PEP? Or is this biologically impossible? 

2. Is there any need, from a medical and preventative standpoint, to tell my partner that I had sex with her while I was on PEP in November 2023? 

3. I read that PEP works by quickly killing any virus that enters my body. Is it possible that there was some virus in my body that transmitted to my partner before the PEP had the chance to kill it? 

1.  No, this is not a scientific possibility.

2.  No

3.  This is repetitive. The answer is not going to change. The answer is an emphatic no

My sense is that you may have been reading about the actions of PEP on the Internet. If you are, please stop. You were being misled . You have nothing to worry about. It’s time to move forward. EWH.