[Question #12687] HIV RNA Qualitative PCR Result
6 months ago
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Good Afternoon, Doctors
Firstly, thank you for offering a service such as this.
Before Christmas I had unprotected sexual intercourse with a former girlfriend as my long-term girlfriend and I had broken up. This was 3 times total in the space of a week and on each occasion I also received oral sex and fingered her vagina.
I very much regret the whole situation!
Since these events, my girlfriend and I have got back together and we are looking to start a family soon. Whilst my former girlfriend said she was clean of STI’s, after the final event she said that she had not been tested for almost 6 months and said she had dated a few men in that time.
I was extremely anxious about this and had an HIV RNA Qualitative PCR test done exactly 21 days after the last sexual encounter. The result came back ‘not detected’ for HIV 1 and 2 RNA.
I have browsed previous replies on this forum and see there is a consensus that these tests are completely reliable by around day 12. However, maybe I just want the assurance from yourselves to my own personal circumstances that I can move on with my life and not have any further lingering fears that I may be infected, or indeed infect my girlfriend.
It is now 91 days since the last encounter and I have experienced no symptoms such as urination pain, body rashes etc. My main fear really is HIV since I know it can’t be cured.
Thank you in advance.
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H. Hunter Handsfield, MD
6 months ago
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Welcome to the forum. Thank you for your confidence in our services.
From what you say about "[your] own personal circumstances, I see little reason for concern. Had I been in your situation, I wouldn't be at all worried about HIV and would not have been tested. There is nothing in your girlfriend's sexual lifestyle, as you describe it, that suggests significant HIV risk -- although the chance of other STIs may be higher.
But perhaps more important, your negative RNA PCR test is 100% proof you don't have HIV. These tests indeed are conclusive 11 days or more after the last possible exposure. As for other STIs, not having symptoms after 3 months is good evidence you weren't infected. However, since youre planning to get back together, I would suggest you both get tested for syphilis, gonorrhea and chlamydia; and that your girlfriend have an HIV test. You can expect her to test negative for HIV, and probalby both of you to tst negative for the others.
I hope these comments are helpful. Let me know if anything isn't clear.
HHH, MD
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6 months ago
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Thank you for your reply, Dr Handsfield. Your comments are very reassuring!
I should have added that I had a blood test taken for Syphilis and Hepatitis B & C 14 days after the last exposure. The results for all three returned ‘non-reactive’, however I had not come across this forum at this point and I have therefore learned it was too soon to test for any of this (yet the Doctor at the clinic I visited said the Syphilis result can be considered accurate?!).
Since these events and the scare they have given me, I have had two doses of the Hepatitis B vaccine (in the UK it was not compulsory for babies in the 90’s like it is now, so I was only given a vaccine for Hepatitis A when I was born). My third and final dose of the Hepatitis B vaccine will be in July this year (I understand there is no vaccine for Hepatitis C, but from reading previous replies in this forum, it is not really transmitted sexually?)
Do you see any concern for Hepatitis in your opinion?
Lastly, am I correct that Syphilis (and other STD’s) can be completely cured with short treatment?
Thank you for your help.
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H. Hunter Handsfield, MD
6 months ago
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The syphilis blood tests are not conclusive until 6 weeks after exposure -- but even without testing the likelihood you have syphilis probably is under one in several million. Hepatitis B also is extremely unlikely; I would not have advised vaccination in this situation, but you are100% protected a month after dose no. 2. True the hepatitis C virus is almost never sexually transmitted between males and females. And yes, syphilis is readily curable with a single dose of penicillin.
You really are overreacting to a near zero risk situation, it seems to me.
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6 months ago
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Thank you once again Doctor for your helpful information.
So in short: move on, all is good?
I do admit that I get anxious around my health. I appreciate the time you have taken to comment.
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H. Hunter Handsfield, MD
6 months ago
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Thanks for the thanks. "Move on, all is good" is a good summary of my advice! Best wishes and stay safe.---