[Question #12799] Oral HSV 2
5 months ago
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Thank you for this service.
I have gotten cold sores since childhood and received a positive, very high, HSV 1 blood test years ago. Over the last decade or so the breakouts have gotten more severe and I started using valacyclovir once daily at 500mg for suppression. That has worked well and I now have few breakouts and they are much less noticeable.
My question has to do with oral HSV 2. I recently kissed someone and, two days later, noticed a new bump on my lower lip which I would associate with cold sores. I did not notice any visible symptom at the time. Is it possible that I acquired HSV 2 in addition to the HSV 1 I already have from the kiss? If it is possible, how likely is it? In your experience, how often have you seen a person acquire oral HSV 2 when they already have well established oral HSV 1?
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Terri Warren, RN, Nurse Practitioner
5 months ago
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HSV 2 is rarely oral, and when it is, it rarely recurs or is shed from the tissues of the mouth. This is something, if I were you, that I would not worry about - at all. The odds of this happening are just so incredibly small. I have never seen anyone acquire HSV 2 orally from a kiss, and I can count on two hands in 40 years, the number of people I've diagnosed with oral HSV 2 at all.
Terri
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5 months ago
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Thanks for this reply. Your experience is reassuring.
Do you have any insight on the work happening to develop an HSV vaccine or treatment? I have read about the work Fred Hutchinson has been doing with gene editing. Is there a breakthrough on the horizon? What are you looking for as the next milestone in these efforts? Clinical trials? What do you consider the best resource for tracking research in this area?
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Terri Warren, RN, Nurse Practitioner
5 months ago
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I think Keith Jerome's work at the Hutch is definitely promising. If you are interested in HSV clinical trials, I would recommend you go to clinicaltrials.com and enter "herpes simplex virus"
Terri
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