6/18 took 800mg cefexime/2g Azith,

6/22 got urine test for gon/chly/trich-neg

6/22 started doxy 100mg bid- still on

6/23 1g rocephin

6/26 1g rocephin

6/29 500 mg rocephin

7/1 1g rocephin

7/2 1 g rocephin

7/5 naat test for gon/trich/chly/myco---(All negative but waiting on mycoplasma)

Still taking doxy bid but still having pain in groin

1)Was the first urine naat test any value?

2)Do you need to wait longer after treatment to test to make sure tests valid?

3)Will treatment affect naat testing? Are you more likely to get a true negative and false positive because of remaining genetic material?

4)Do you have to be off treatment for some time to believe a neg test?

5)Is the problem with the way I have been treated and tested the fact that I will never know if I truly do/or did have anything to begin with?

6)Can I believe my tests 100% that its a true negative and that I CURRENTLY dont have got/trich/chly?

7)Do I need to retest for test of cure or retest any more because of the way treatment and testing done?

I am waiting on my urology visit at the end of the month....earliest

Thank you very much

Wow! In the 21 years of this and our preceding forum -- and after 50 years in the STD business -- I have never encountered such a story or gross over-treatment and over-testing, even after multiple exposures and certainly not for a single exposure. I would be happy to comment further if you would like to describe the details of your exposure June 14, but most likely you have gone way overboard with testing and preventive treatment. If you decided on these approaches yourself, you clearly have serious misunderstanding of STD risks and appropriate prevention and testing strategies. If your urologist or other doctor has recommended all this, I have to seriously question his or her understanding and clinical judgment. I have never hears of such gross over response to a single sexual exposure, regardless of the frequency of various STDs where you reside or the nature of the sexual exposure. 

1,5) Having taken cefixime and azithromycin 4 days before being tested, your test results 8/22 show you were not infected at the time of testing, but in theory you could have been infected and the antibiotics aborted gonorrhea and/or chlamydia. As noted above, in my entire professional life (50 years in the STD business), I have never heard a story like this one.

2-4) Yes, your major over-treatment with antibiotics definitely affects NAAT testing. With all those antibiotics, all the tests you describe were pointless and there definitely is no need to be tested again at any time for gonorrhea, chlamydia, or syphilis. 

6) The negative test results will be true negatives.

I see no need for another urology visit and would be inclined to avoid that doctor or the clinic where you have been evaluated.

I hope these comments are helpful. Let me know if anything isn't clear.

HHH, MD

1)Without treatment, how soon is too soon to test after an exposure for gon/trich/chly with urine NAAT?

2)Would have the quick treatment I had killed early syphilis if there?

3)If one gets treatment like I did, does it cause confusion by potentially killing an infection that may or may not have been there? Is that the issue?

4)Is the concern about not getting tested until AFTER TREATMENT, the fact testing provides less value?  I negative, can one believe, but if positive still, you have to wait longer and test again to make sure all infection is killed?

5)Sources say to wait three weeks and maybe even 3 months to after treatment to test again.  Why is that?  Leftover genetic material causing false positives?

6)IF you test like I was tested, THREE WEEKS after exposure and after multiple rocephin shots(See timeline above), and currently taking doxycycline still, does that alter the confidence of the all NEGATIVE results?

7)I understand Cefexime not a good first line treatment for Gonorrhea, but still could have aborted infection before it "got going"?

8)How confident would you be in all my testing I had at THREE WEEKS after exposure and all being negative even with all the treatment?  Is there any chance I have gon/chlyamidia/trich with all my tests?

9)You said the NAAT test I had were not very useful/pointless, why is that the case?

10)LASTLY, Am I TOTALLY SAFE in regards to above questions, to have sex with my wife without fear of infection to her?

Thank. you

If you could please address those previous questions in prior reply, that will complete my thread. 

I really need to be over this. 

Thank you

1) 4-5 days.

2) Yes.

3) The treatment made it impossible to ever know if you were exposed or infected.

4) Irrelevant.

7) Wrong. Cefixime is very good treatment and completely effective as prevention after exposure.

9) Because you were treated before being tested.

10) Yes.

That concludes this thread.