Hello Drs and thank you for the service you provide. I’ve already used this forum to conduct my own research regarding my situation and am likely aware of the answer I’m going to receive but am asking to ease my own anxiety. I am a male and  recently received unprotected oral sex from another man I met via an online cruising app. The other man seemed affluent, clean, and is approximately 45 years old. I am a married man and felt immediate anxiety about what I had done and the potential of exposing myself and my partner to an STI. I already knew the exposure was low risk for HIV but I became paranoid about chlamydia and gonorrhea. I was prescribed doxypep by a telehealth provider and took it the day after the exposure. On day 7 after the exposure I took a home urine naat test by a mail in testing company that just came back negative today on day 10 for gonorrhea and chlamydia. I have no obvious discharge or urinary pain but do have some “Minty” sensation at my urethra that I think could be anxiety. Is a 7 day mail in urine test enough to put this behind me and move forward with my wife or should I wait to be retested again at 14 days? Assuming gonorrhea would have been obvious by this point. 

Welcome back to the Forum.  On this occasion I happened to pick up your follow-up questions and will be responding (in addition, this response is coming more quickly than is typical- I happened to be on the Forum when your questions came in.  Further follow-ups may take longer).  In preparing to answer your follow-ups, I reviewed your interaction with Dr. Handsfield and agree with all that he said.  I would now encourage you to have complete confidence in the results of your recent urine NAAT tests following your casual encounter.  The medications you took would have prevented any infection that you might have been exposed to from taking hold.  The combination of coxy-PEP plus cefixime and subsequent negative tests provide virtually incontrovertible proof that you were not infected and need not test further.---

I appreciate your thoughtful reply. I guess I should just trust my negative tests and put this whole thing behind me. I had a negative 7 day test as well as a negative 14 day test but had sex with my wife on day 12. It would be highly unlikely to be contagious with either GC or chlamydia on day 12 and then test negative at day 14 right? Can you share any insight on how crucial it is that the urine tests be done without urinating prior? I urinated about 20 minutes before I took the day 14 test. 

Thanks for the additional information.  With your tests, I would be confident that I was not infected.---