[Question #13511] STD Outbreak

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3 days ago
I am a 30 year old heterosexual male, only normal Intercourse.

In October 2024 I had unprotected sex with a friend who told me she was clean and In May 2025 I had a second encounter and waited 3 weeks exactly for testing before having sex. PCR Panel, blood and urethral swab. It came back negative for over 40 HPV subtypes, unfortunately HPV 73 came back positive and for mycoplasma hominis and ureaplasma.But Negative for chlamydia, gonorrhea, syphilis, herpes both types. 

MyEX, just had positive for chlymedia, an outbreak of warts all over her vaginal/anal area and 1st and 2nd grade cervical lessions. Adding to this the fallopian tubes damaged. Always regular paps and last one was on March, everything in order. Also in less then a month she went from having 2/3 warts to have all her area covered. 

In those 2 years I had few occasional sex with her, most recently around 3 months ago. No signs or warts, only a black spot that I've had for over 6/7 years.

Any ideas why the sudden outbreak?

Thanks
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H. Hunter Handsfield, MD
2 days ago
Welcome to the forum. Thank you for your confidence in our services.

First issue is your test results in May or June. It's good your tests for important STIs (gonorrhea, chlamydia and syphilis were negative.  Ureaplasma and Mycoplasma hominis are normal bacteria in the genital tract. Over half of all sexually active persons test positive for one or both. In absence of symptoms, you should not have been treated. Herpes testing also is not recommended in people without symptoms but the negative result might have been reassuring.

The positive result for a single uncommon type of HPV is meaningless and nothing should be done about it.

It is clear your ex partner has chlamydial pelvic inflammatory disease (PID), the most common important complication of chlamydia (as well as gonorrhea). You can safely assume she has had sex with someone else since you did; he is the likely course of her infection. Having last had sex with her 3 months ago, you could consider retesting for chlamydia now as a precaution, but most likely you don't have it. Her genital warts probably have nothing to do with your positive result for HPV 73. You should be on the lookout for warts over the next couple of months, but probably it's not a problem for you. Neither warts nor any other STI is a likely cause of a "black spot" in the genital area.

A final consideration is whether your former partner's recent STI testing included HIV. That's one possible explanation for rapid development of a large number of genital warts. And of course HIV testing should be done whenever anyone is diagnosed with any STI. You might also consider testing as an option; the chance you have it is very low, but better safe than sorry.

I hope these comments are helpful. Let me know if anything isn't clear.

HHH, MD
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2 days ago

As soon as I had knowledge about the situation (10/17/2025)I offered my self to go with her and have some std panel for my self as well. I came back negative for HSV1/2, HIV, hepatitis b and c negative as well. Negative for syphilis as well. She came back negative for all that as well, besides Chlamydia. But for chlamydia the lab did Elisa test and came up with IgG and IgM. IgM came up with .32 Du/ML being >1.1 positive and .9 > negative. While IgG appear 2.16 Index being  >1.1 detected and .9 > not detected. ( Hers came up same on IgG 2.16 but IgM came as 1.20 Du/ML) 
I am very confused with the results, I went last week (10/22/25)  to re do the chlamydia test but through urine PCR test. I'll have results later this week. Either way I am already taking doxycycline 100mg every 12 hours planning to complete a full week. 

The interesting part is that I could tell you with certainty that I’ve been here only sexual partner. Although we weren’t together for over two years. 

1. My major fear is that maybe I had chlamydia from long time before and I infected her in some point. (No symptoms + PCR Negative). Is it common for chlamydia to behave so aggressive in that short time? Or is it possible to be in the body and suddenly react that way after couple months? 
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H. Hunter Handsfield, MD
2 days ago
It certainly is possible for chlamydia to have such "aggressive" outcomes in a short time. However, the blood tests for chlamydia are not reliable and are not recommended by STI experts. Your partner's positive test result might be from an infection sometime in the past, not a current infection. I do not understand why she had only the blood test but you have had a PCR test. Probably your test result will be negative. However, to be safest, I agree with your treatment with doxycycline. Whether your result is negative or positive, you'll need to discuss the results with her doctor and yours. I'm sorry I cannot be more helpful.---
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2 days ago
Just to clarify I am the one that had the reactive IgG and negative low IgM levels. (She had both positives) So by you saying about a past infection you ment me? 

Just to clear my mind, the 3 weeks I waited on may for the PCR std panel was a good time frame? Specially for chlamydia. 

I have had a casual sex with a friend for over 2 years, after my May exposure, I stoped sex with here for prevention and resumed sex after my results in June. Until now se has not mentioned any discomfort of nothing unusual. Although I have not had sex with her for over a month but definitely multiple times after my results in June. 

Would you recommend me to disclose the situation with her? Primarily health-wise. Given that I might actually have it, her absence of not having symptoms is a good indicator? 


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H. Hunter Handsfield, MD
2 days ago
Sorry I misunderstood, but even with careful re-reading it appears you were describing your partner test result. Your blood test could indicate recent chlamydial infection and you may have been the source of your partner's infection after all. Sorry for transient confusion on this. You and she both need to complete your doxycycline prescirptions.
There remains uncertainty which of you had chlamydia first and who infected whom. If you both are infected, there is at least one more sex partner -- his or hers -- who has been involved. That person also must be identified and treated.

This situation is very confusing and I cannot be the source of figuring out the details. This will be up to you, your partner, your doctor(s), and any other partners either of you have had in the past few weeks or months.

That completes the two follow-up comments and replies included with each question and so ends this thread. I hope the discussion has been helpful. Best wishes and stay safe.Good luck. 

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