[Question #13526] Follow up - [Question #13511] STD Outbreak

Avatar photo
1 months ago
Sorry for being messy on my explanation but was trying to give full context and not miss anything out. 

Update,  I had Urine PCR Test for Chlamydia and Gonorrhea on Oct 24 and got my test back on Oct 30th, they came back negative. 

In September 1st I had a broken wrist surgery and was prescribed for 6 days twice a week 1gr of Cefalexin 

On October the 8th I had my wise teeth removal and was prescribed with Amoxicillin for 7 days twice a week 500mg 

My ex did test positive for Chlamydia on the Elisa Test On October 17, 2025
IGG Index 2.14 where >1.1 Detected 
IGM 1.15 Du/ML where <.9 Negative 
(Last vaginal sexual interactions late July) 

October 17, 2025, my results for Chlamydia on the Elisa Test were ;IGG Index 2.11- IGM .34 Du/ML.

What is the probability that this medications might have affected my results both the ones on October 17th and 30th? 

Is it common or possible for IGG values come wrong of falsely detected? How long do they last in the system? 

Is there such thing as being chlamydia positive for a long time and not being transmissible to others? Or getting active because of being immunocompromised? 

Avatar photo
Edward W. Hook M.D.
1 months ago
Welcome back to the Forum.  On this occasion I will be answering your follow-up questions.  In preparing to respond, I reviewed your earlier interaction with Dr. Handsfield and agree with all that he said.  Let me re-emphasize Dr. Handsfield's statement that in general blood tests are not reliable for diagnosis of chlamydial infections- the can be falsely positive and persons who have had chlamydia infection in the past can have positive test results even when they are not infection.  Both IgG and IgM tests are unreliable and IgM tests are even more unreliable than IgG tests.  The proper test to look for chlamydial infection (as well as gonorrhea) is a PCR test of the sort that you had on October 24.  Your October 24 test provides PROOF that  did not have chalmydia or gonorrhea at that time.  Your ex may or may not have had chlamydia but you do not.  

Cefalexiin had no activity against chlamydia and amoxicillin may suppress chlamydia but that does not change the fact that your recent chlamydial PCR PROOVES that you were not infected at the time you were tested (both on October 17 or on October 24.  

As I explained above, the IgG tests you mention could be falsely positive or could be the result of an infection in the distant past which is no longer present.  

When chlamydia infection is present, it can be transmitted to others although not every exposure to an infected partner results in transmission of infection.  Each exposure leads to transmission, on average, about 20%of the time.  Being immunocompromised would not cause chlamydial infections to re-activate.

In summary, one thing that you can be confident in is that you do not have chlamydia at this time.  EWH
---
Avatar photo
1 months ago
Follow up Question, 
By you mentioning a possible suppression by taking amoxicillin would that cause a negative result on my tests? 

Would you consider proper health-wise making my current sexual partner aware of the situation so she can get tested? I don’t wan to cause her unnecessary anxiety, but if there is a probability I’ll definitely do it. Last multiple sexual intercourse  with here occurred over a month ago, no signs of symptoms. Saying this, if you do have symptoms; can they stop by taking some other medication (UTI’s medication)  while obviously keeping the virus active? Or do symptoms just appear and can disappear later on? (without medication). Trying to understand how chlamydia works.  

Can I purchase another question but related to HPV? Or is it against rules? 

Appreciate the answers doctors. 



Avatar photo
1 months ago
Little typo; I meant “with her” and by no symptoms I meant from her side. (Neither mine) 
Avatar photo
Edward W. Hook M.D.
1 months ago
Dr. Handsfield and I have discussed your questions in depth.  Beyond the information we have provided, there is little more that we can say to help sort your concerns out.  We advise you to seek the input of a specialist who has complete access to your records and who can examine you.  There is little more that we can do to help you through this on-line advice Forum.  I'll provide brief follow-up to your follow-up questions where there are clear answers:

1.  By you mentioning a possible suppression by taking amoxicillin would that cause a negative result on my tests? 
Response- no.  You should believe your test results

2. Would you consider proper health-wise making my current sexual partner aware of the situation so she can get tested?
Response- no!  You have proven that you do not have chlamydia with your negative PCR tests.  Believe your test results.  Symptoms and signs of infection do not come and go

We ask clients to keep questions on a single topic.  If you have questions about HPV you should ask another question but I hesitate to advise you to do so.  Instead I suggest that you look at past interactions with other clients on the topic of HPV- there are hundreds of them.  One follow-up remaining.

EWH
---