[Question #1602] Equivocal hsv 1

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92 months ago
I was tested for herpes 1 and 2 at 12 weeks post exposure. The results were negative. Only symptoms I know of that I've had were red scrotum and extreme dizzy spell with vomiting. Red scrotum hasn't gone away. I went to get tested again because of paranoia. No recent exposure. This is now 15 weeks and the test for hsv 1 came back equivocal at .95. I know equivocal means neither positive or negative but I have spent a lot of money on testing and this forum now. I just want to put this to bed. The stress and panic is unbearable. Please help. 
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92 months ago
I talked to the testing company. They said hsv 1 was just under .91 the first test at 12 weeks and now at 15 weeks its .95. Just wanted to add this to clarify. 
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Terri Warren, RN, Nurse Practitioner
92 months ago
I think you should be focusing a bit more on the HSV 2 result which was negative,  The majority of the population is positive for HSV 1.  You are equivocal now for HSV 1 and you may well have HSV 1.  Have you ever in your life had a cold sore in your lip, even as a child?  If yes, this would explain the possibility that you are infected with HSV 1.  As I think we've discussed, the screening IgG test misses 30% of HSV 1 infections, so the test results that you have for HSV 1 is not fully reliable - the herpes western blot is more accurate for both HSV 1 and 2.  That is the test that will tell you for certain if you have or don't have HSV 1.  The red scrotum has nothing to do with HSV 1, so if you are trying to sort that out, this isn't the way to do that.  I'm sorry that you've spent a lot of money on testing and this forum - I believe that was your call to make - and now if you really want to know if you have HSV 1, you'll need to spend more money on a western blot, which is around $200.  Or can you accept that you may have HSV 1 infection and decide to live as though you do.  That doesn't involve any further expenditures.  The lack of clarity of the testing is just a lack of the test's ability to give a clear answer - it isn't anyone's fault. 

Terri
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92 months ago
Does the equivocal value of .95 mean I'm converting to positive? Hsv 1 I understand is with cold sores or the mouth. Hsv 2 with genital herpes. The partner I know had herpes on her genitals. Could you provide me with some information on that?
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92 months ago
I don't remember having a cold sore. On lips I am unsure. But definitely none on my genital area. No blister or bumps whatsoever. 
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92 months ago
Partner from 15 weeks ago is confirmed to have hsv 2. Since I've been negative for that at 12 and 15 weeks that should confirm I don't have genital herpes. Correct? HSV 1 being positive is likely due to mouth sores as a kid and not remembering. Correct? No other partner that I'm aware of has had any hsv 1 or 2 to my knowledge. I just want to rule out genital herpes. 
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Terri Warren, RN, Nurse Practitioner
92 months ago
I believe that with 95% certainty, you are HSV 2 negative. correct. 
It's more difficult to answer with any certainty if you have HSV 1 or not.  With an equivocal .95, I just don't know if you are infected or not.  If you are, and you've had neither a cold sore nor any genital lesions, we cannot know where your infection is located in your body.  HSV 1 can be genital.  Without a herpes western blot, we cannot know for certain if you have HSV 1 and even with that, a positive test cannot tell you the location of your infection.  Statistically, if you have this, it is probably more likely oral than genital but without sores in either location, we cannot be certain. 

This is your final post on this thread.  I really don't have any more to offer you on this problem and I know it is difficult to have some unknowns here.

Terri
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