[Question #2066] Herpes Testing

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83 months ago
Culture tested positive 15yrs ago and 2 recently taken IGG test showed negative for herpes 1 and 2 antibodies.  I have had what I believed to be outbreaks over the years but now Im confused as to if I really have it or not.  After so many yrs of having herpes does it dissappear in blood test or make it harder to detect?
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Terri Warren, RN, Nurse Practitioner
83 months ago
Well, that could be the case, and that is called seroreversion but the more likely thing is that you have HSV 1 infection genitally.  The IgG test for HSV 1 misses 30% of infections, 8% of HSV 2 infections, these compared to the gold standard western blot.  I take it that no one typed your swab sample 15 years ago?  It turns out to be pretty darn important, what type you have.  Do you know?  May I ask why you recently did the IgG test, to find out the type?

Terri
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83 months ago
I paid for a test panel that covered all STD's to make sure I had not contracted anything else and IGG testing was part of it.  No they didn't test to determine the type 15yrs ago and since the IGG test are coming up negative to HSV 1 & 2 im not sure what type I have.
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83 months ago
Where or how can I take the western blot test to be get more accurate results?
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Terri Warren, RN, Nurse Practitioner
83 months ago
I can help you get the western blot or you can go through your regular health care provider.  You need to send for a kit from the University of Washington - call 206-685-6066 for the kit - then you will need a clinician to order the test for you - you cannot order the actual test for yourself.  If you want to do it with me, you can set up a video conference with me by going to my website, westoverheights.com and we will discuss it and I'll get some history and I'll order it for you and send you a lab requisition to go in the kit with my information.  Then you find someone who will draw and spin your blood and you'll ship it back to UW.  I think you are wise to try to sort out what type you have.

Terri
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