[Question #2195] Hiv test conclusive

48 months ago
Hello Doctors 

I have a concern from athe following exposure.
Im a male and I received unprotected oral sex to my penis from a female with unkown Hiv status and a comdom break while having vaginal sex for about 10mins at the most.
I have been concern so I had an Hiv RNA test 4 weeks and two HIV 4th gen/combo at 6 weeks.
How conclusive are my results at this times from the exposure.

4 weeks Quest Diagnostic HIV RNA qualitative : Non Detected

6 weeks Quest Diagnostic: HIV 4th gen combo test: Non reactive 

6 weeks Labcorp: Hiv 4th gen combo test- None reactive 

1.How conclusive are my results at this times from the exposure Do I need to test up to 12 weeks?
2. Can I be 100% I dont have HIV and move on.


H. Hunter Handsfield, MD
H. Hunter Handsfield, MD
48 months ago
Welcome fo the forum. Thanks for your question.

You were at risk for HIV, which has never been reported to have been transmitted mouth to penis. The condom break in vaginal sex was risky, but the large majority of sexually active women don't have HIV, so the odds are you were not exposed. 

But the direct answer to your question is that your test results are conclusive. The 4th generation (combo) test is usually conclusive by 4 weeks and always by 6 weeks after exposure. Your repeatedly negative tests prove for sure you did not catch HIV. Advice to test at 12 weeks used to apply to the older antibody-only HIV tests. With the combo tests, which detect both HIV antigen and antibody, there is never a need to test beyond 6 weeks. So for sure you can be 100% certain you don't have it and can move on without worry.

You don't mention testing for other STDs, which are much more likely than HIV. If you haven't had a urine test for gonorrhea and chlamydia, and a blood test for syphilis, I recommend you do so.

I hope this information has been helpful. Let me know if anything isn't clear.

48 months ago
Thank you DR. Handsfield for your answer.

Sorry I did not metion I did take a urine test for gonorrhea and chlamydia at 3 weeks. Negative

1.If a take a blood syphilis test now at 6 weeks and 2 days from exposure would it be conclusive?

2. As far as reciving oral sex.  You mention its no risk. 
Is that because saliva doesn't transmitted hiv to the penis? 
H. Hunter Handsfield, MD
H. Hunter Handsfield, MD
48 months ago
1) Yes, it will be conclusive.
2) There is little HIV in the oral cavity, and saliva kills HIV. Oral exposure of any kind (e.g. kissing) rarely if ever transmits HIV.