[Question #2291] Naat test for gonorrhea and clamydia

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98 months ago
Hello Doctor, 
I recently received oral sex from a woman of unknown status who claimed she did not have anything.  I'm sure this is probably a low risk event but I tend to be a germaphobe. 
This was Friday night and today, (Tuesday), I went to Quest labs and gave a urine sample for a Naat test for both gonorrhea and clamydia. 
My concern is that the lab tech told me to do a clean catch (midstream) instead of the first void collection in my urine sample. I was puzzled as I understood first void collection to be the standard for this test. I did not void very much before urinating into the sample cup.  Will this make a difference in how reliable my test results are? My fear is a false negative because of this. 
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H. Hunter Handsfield, MD
98 months ago
Welcome to the forum. Thanks for your question.

As you perhaps know from reading other questions like yours, oral sex is safe sex, with a low risk of all STDs and zero risk for some. The chance you caught gonorrhea is very low and chlamydia close to zero. (There have been few if any proved cases, ever, of oral to penile chlamydia transmission.)

The NAATs for gonorrhea and chlamydia are very forgiving. When they first became available 20 years ago, the initial research specified first void rather than midstream urine specimens. Because that is how the tests were studied, the official marketing advice (by FDA regulations) specify first void. However, this doesn't mean that midstream specimens are not just as good; they probably are, and although in our STD clinic we ask patients to collect the first ounce of voided urine, I'm sure many misunderstand and we make no attempt to monitor it. In other words, the lab tech was wrong; but it probably dosn't matter much. However, you might do him or her, and the lab, a favor and send a printout of this discussion. Even if it doesn't really make much difference, they should follow proper test procedures!)

A more important issue is the timing of your test. The gonorrhea component of the NAAT probably is fully sensitive by 3 days, but it may take a bit longer for chlamydia (e.g. 5 days). OTOH, as noted above, there is no realistic risk of chlamydia from this exposure. But I thought you should know.

I hope this information is helpful. Let me know if anything isn't clear.

HHH, MD

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98 months ago
Thanks for that info Dr Handsfield.  I do understand that this was a low risk situation but the fear of catching gonorrhea and reading about how that can be passed by oral sex gave me some anxiety. 
Given my situation, would you recommend that I retake the test in a couple of days or do you think that  it is totally unneeded?  
I have had a slight increase (or perhaps that is my perception) in urination but I think that is my anxiety/guilt kicking in. I have not had any sort of discharge or burning pain although it maybe a bit too soon for symptoms and I know some people are asymptonatic.  I don't want to pass anything on to my wife. 
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H. Hunter Handsfield, MD
98 months ago
I do not recommend being tested again. Assuming "increase in urination" means more frequent, for sure no worries: neither gonorrhea, chlamydia, nor other STDs cause more frequent urination.

It's not too soon for gonorrhea symptoms, which usually would have started by now. Although asymptomatic gonorrhea occurs (I am the first modern researcher on asymptomatic gonorrhea in men), it is rare:  at least 95% of urethral gonorrhea causes obvious symptoms. Let's do a quick probabilities analysis:  chance your partner had oral gonorrhea, probably no higher than 1%. Chance you caught it if she had it, 10%. Chance you were infected without symptoms, 5%. Chance the urine test missed it:  1%. Thus, the chance you now have urethral gonorrhea is 0.01 x 0.1 x 0.05 x 0.01 = 0.0000005. That's 1 chance in 2 million. In other words, zero.

If somehow I had been in your situation, I would not have been tested at all and I would never have stopped having sex with my wife. You can and should proceed without worry.

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98 months ago
Ok I am relieved that I'm in the clear for gonorrhea as my tests both came back negative yesterday.  however, would you say I'm not officially clear for chlamydaia as far as testing goes?
 I do realize that it is a lesser risk but she did "deepthroat" me and I figured that may have brought me closer to the source of bacteria if she had it. She and her husband are swingers but claim to get tested often. Does that change your opinion on me retesting?  
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H. Hunter Handsfield, MD
98 months ago
More vigorous or "deeper" oral sex is not know to increase the risk of STDs. You can be sure you do not have chlamydia. The test alone is not the only reason. I base it on 1) oral/throat chlamydia is rare, 2) if present is rarely transmitted, plus 3) the test. Even though the test was a bit early, most infections still would be detected at 3 days. I recommend not having any further testing and moving ahead without worry.

That completes the two follow-up comments and replies included with each thread, and so concludes this discussion. Best wishes and stay safe!

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