I took a 4th generation test yesterday ( HIV DUO ) and I had taken the same one 4 months back. Both non-reactive.

But the i dont understand the reports.

the First test: Non-Reactive (0.10)

Yesterday's Test: Non-Reactive (0.26)

What does the difference in the value mean? I do understand that I'm free from infection, but does the increase in number mean I've a chance to show seroconversion on future?

Also, my Absolute Lymphocyte Count is 3330 cells/cu.mm and the percentage of lymphocyte  cells is 45%. I dont have any symptoms at the moment and feel just fine.

Can you please help me out understanding the significance here? Is this lymphocytosis? 

Thanks.

The difference in the numerical test value means nothing. Every result below the posiitve cut-off is negative. It's baked into the biochemistry of the test:  the very same blood specimen tested 10 times, with different batches of test reagents, will give 10 different numbers. Your two results are equallly valid and negative.

And there was no point in having a blood count. Your lymphocyte count adds nothing to the determination of whether or not you have HIV. And your result is normal; you do not have significant lymphocytosis. And if you did, it would mean nothing in regard to HIV. Only the HIV test result itself is pertinent.

So all is well. Don't have any more tests of any kind.

I hope this information is helpful. Let me know if anything isn't clear.

HHH, MD

Regarding my lymphocytes.. It came back highlighted on my reports saying upper limit being 3000 cells. and upper limit for % being 40% .

I tried reading a lil about it, but the internet has left me so confused. some say 3000 cells and some sites say 4000. reading the differential diagnosis worked me up even more. I understand from what you mentioned above that this has no significance with HIV. But I would really feel fortunate to have an approximate reference range for the lymphocytes from you. Do I need to follow up with my CBC? Also, I'm an Indian- American, dont know if the race matters so just mentioned it. Thank You for your explanation. You and Dr. Hook have made things so much simpler for so many of us. Commendable. Thanks again.

Healthy people who feel well generally should avoid having routine blood counts and blood chemistry tests, especially on their own initiative. If recommended by your doctor on the basis of symptoms or examination findings, that's obviously different. But testing in outwardly healthy people often shows minor variations that are meaningless. That's what's going on here.

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