[Question #3006] General Question/Education

39 months ago
Dr’s,

I have a general question that I would like to have one of you experts in the field answer. I realize there are two different types of retroviruses ie. (Endogenous and exogenous).  Endogenous being in our DNA and not pathogenic whereas Exogenous can be transmitted from human to human ie. HIV and HTLV.  Are these the only two retro viruses that are known to be transmitted sexually (HIV, HTLV)? I know there are some controversial issues out there regarding MLV’s/ XMRV and the research that was conducted and also retracted by Judy Mikovits among others on these viruses. Maybe one of you can expand on this and your experience with such issues. Thanks in advance for your responses. 


Edward W. Hook M.D.
Edward W. Hook M.D.
39 months ago
Welcome to the Forum.  With the important caveat that neither Dr. Handsfield not I are clinicians, not virologists, much less human retrovirologists,  I will provide a brief comment.  Retroviruses, as both exogenous viruses which can be transmitted from person to person but also endogenous, retroviruses which are estimated to comprise 5-10% of the human genome have generated considerable interest as potential causes of human diseases.  There are also a number of exogenous animal retroviruses which have been described but to my knowledge, the major human transmissible retroviruses are in the HTLV and HIV families.  XMRV was studied carefully as a cause of chronic fatigue syndrome and proven NOT to be related to the problem.  Dr. Mikovits played a central role in introducing the possibility of XMRV however her work was later disproven and had to be retracted. 

As a more general comment, it is my sense, based on no data, that there are certainly persons who have signs or symptoms which are not readily explainable on the basis on currently identified pathogens, whether those pathogens are bacteria, fungi, viruses, retroviruses or other life forms.  Such persons are sometime vulnerable to suggestions that there problems may be due to infections such as those due to retrovruses based on limited and sometimes questionable data.  As such they are a deserving target for study but should be approached with caution by any individual.  For such persons, it is also sometimes frustrating that the potential pathogen of interest for them may not be prioritized as a research topic.

I am not sure if this perspective is helpful to you or not.  Here in this Forum we do our best to base our responses on a combination of information we have gained from the published, peer-reviewed medical and scientific literature, knowledge gained from attendance and participation at scientific meetings, and our combined more than 70 years of direct experience in caring for persons with and at risk for STIs.  EWH
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39 months ago
Dr. Hook,

Thank you for your insight. I can’t say that I’m satisfied but I understand that it’s not as simple as a “yes or no” answer as there are many unknowns. In all your years of experience as well as speaking to colleagues have you come across or heard of an individual who had contracted a retrovirus sexually that was outside of the HIV and HTLV realm? 
Edward W. Hook M.D.
Edward W. Hook M.D.
39 months ago
By way of follow-up, after writing the response above I went back and searched for earlier posts from you and reviewed your two earlier interactions with Dr. Handsfield.  I do not think that anything I said above is inconsistent or out of line with your prior interactions with Dr. Handsfield and I agree with his counsel to you as it related to your specific concerns described in those posts.  Be cautious about suggestions made as to pathogenetic processes described on the internet and detection of new symptoms which might simply be a reflection of close inspection leading to noticing the sorts of personal cutaneous and other irregularities we all have which had been unnoticed in the past, prior to a period of more intense scrutiny.  EWH
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Edward W. Hook M.D.
Edward W. Hook M.D.
39 months ago
Our responses to each other crossed.  No I have never encountered or heard of a person in whom sexually  transmitted retroviruses other than HTLV or HIV have been sexually transmitted.  EWH
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39 months ago
Dr. Hook,

Thank you for your responses. I will do my best to stop thinking I have something that the science field/health field are unaware of. 
39 months ago
Dr. Hook,

Just wanted you to see a message from Dr. Mikovits that she sent directly to me regarding XMRV.  Surely you can see why I have reservations of who to believe.

The Imminent virologist likely the fraud Lipkin
Only in the last few weeks have i been able to confirm how they committed the fraud of the so Called Lipkin study or How about Criminal Tony Fauci
We can help you and your family and we are doing everything possible to bring these criminals to some justice.



39 months ago
I did NOT GO ALONG with the RETRACTION of our Paper  I was Jailed because I REFUSED To retract our work. IT WAS RETRACTED WHILE I WAS HELPD IN JAIL ON A FALSE ARREST AND DR BRADSTREET WAS KILLED! 
And As For the Lipkin Study We are all FLAT OUT LIED TO BY FAUCI AND LIPKIN ..they lied about the data and used fraudulent statistics to remove the association
Just as Lipkin and the federal government did with Andy Wakefield (read Inoculation Kent’s newest book and you will see it all

I LOST EVERYTHING DEFENDING THE TRUTH AND CONTINUE TO DO SO EACH AND EVERY DAY OF MY LIFE. I DID NOT DO THIS TO YOU LOOK AT THE LAST SLIDE OF THAT PRESENTATION AND YOU WILL SEE WHO INFLICTED THIS ON YOU AND YORU FAMILY THEY CONTINUE TO DO SO


There are cures for you and your family just like there were cures for the HIV/AIDS victims of the first plague of corruption. Direct your anger at the real criminals 
Or write Ian Lipkin and Tony Fauci and see if they answer you..They haven’t said a word about our book where they are quoted perpetrating the fraud !!
39 months ago
Meant what to believe not who to believe.
Edward W. Hook M.D.
Edward W. Hook M.D.
39 months ago
I understand how strongly expressed beliefs can be persuasive.  At the same time, scientific progress has moved forward through a process called peer-review in which scientists independently evaluate each others' work.  For better or worse, her peers have evaluated Dr. Mikovitis' work and not found it persuasive, questioning the methods through which she and colleagues came to their conclusions.  Others have independently worked to replicate Dr. Mikovits' work and been unable to do so. 

I agree and with your earlier statement and would encourage you to "best to stop thinking I have something that the science field/health field are unaware of".  At present there are no recommended tests or therapies for XMRV.

With that this thread will be closed.  Unless there are new data published to suggest otherwise, the advice Dr. Handsfield and I have provided represent our bet advice.  I wish you the best.  EWH
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