[Question #3028] Follow-up

41 months ago
Dr. Hook, just checking back in. Took my daughter to an ID specialist and she was given a tppa test. It was negative. How accurate/ reliable is this test for late CS? Also, she has taken amoxicillin for strep throat in the past. Would this have cured it and given her the negative tppa? Or is this negative tppa absolutely conclusive that she never had CS?
41 months ago
This is a follow up to question 2746
H. Hunter Handsfield, MD
H. Hunter Handsfield, MD
41 months ago
Welcome back to the forum. I'll be answering your question this time, but I reviewed your earlier discussion with Dr. Hook. I'm sorry you found it necessary to return after the reasoned, science based reassurance you had from Dr. Hook. I agree with all he said:  there was no realistic chance your fellatio partner had syphilis, you for sure were not infected, and there was no significant possibility your child was infected. In any case, to answer your direct question this time:  your child's negative TPPA indeed proves he does not and never had syphilis. Previous antibotic therapy makes no difference; in anyone who has ever had syphilis, TPPA and other "treponemal" blood tests are positive for life, so a negative result proves the infection was never present. I'm sure your child's ID specialist said much the same.

I hope this settles thing for you. Let me know if anything isn't clear.

HHH, MD

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