[Question #3408] Question

37 months ago
Hi Doctors,

Thank you for providing this platform to ask questions. I just wanted to ask a few quick questions (please excuse if they are not rational, but i think sometimes we just need to know real facts)

1) i had about 4 tests done (1/2 Abs and P24Ag) over a period of a few months and all of them had the EXACT SAME figure on the result; is this common and have you seen such occurrences?
it was below 0.3

i do not reside in the US, but the lab was CAP certified, not such if this really matters, but just wanted to lay it out there in terms of the reporting

i asked the lab about this, and they were like your the same person and it just means its stable, i.e. the results

2) is the test just intrepeted always in terms on reactive or non reactive universally ? or do the numbers also have any significance ?

3) do you need further details regarding the exposure etc?

Edward W. Hook M.D.
Edward W. Hook M.D.
37 months ago
Welcome to the Forum.  I happened to be on the forum and saw your questions so you are receiving replies more quickly than is usual.  If needed, follow-up replies will not be so quick.   I'll be glad to address your questions.

1) i had about 4 tests done (1/2 Abs and P24Ag) over a period of a few months and all of them had the EXACT SAME figure on the result; is this common and have you seen such occurrences?
it was below 0.3
Your test results are unequivocally negative.  Tests for both antibodies and antigens have what is called a "lower limit of detection" which is effectively but not chemically zero because many specimens have a small amount of reactivity which is registered by the test.  Your background activity is so low that your specimen levels are below the test's lower limit of detection which for practical purposes is zero.  You should have confidence in these test results and unless you have  additional exposures of concern, additional testing is a waste of time and money. 

i do not reside in the US, but the lab was CAP certified, not such if this really matters, but just wanted to lay it out there in terms of the reporting
The CAP (College of American Pathologists) certification is the highest standard of laboratory approval and should give you confidence in your results. 

i asked the lab about this, and they were like your the same person and it just means its stable, i.e. the results
I agree.  You should believe your test results.

2) is the test just intrepeted always in terms on reactive or non reactive universally ? or do the numbers also have any significance ?  

The numbers are useful within the laboratory for quality control of procedures but the numbers are of no meaning for any individual person.  Negative is negative irrespective of the value.

3) do you need further details regarding the exposure etc?
With these sorts of results, obtained on multiple occasions more than six weeks after an exposure, details of the exposure are not needed unless you have taken anti-HIV medications.

I hope these answers are helpful and reassuring.  From what you have written my sense is that you can move forward without further concern and without a need for additional testing.  EWH
---
37 months ago
Thanks alot for taking out the time to give such a detailed response, much appreciated

If it’s okay, just wanted to ask a few quick things as a summary

in the second point, you mention for quality control for a lab, numbers may matter; so having an EXACT SAME result of 0.25 in four tests will not fall under flag right due to the points you mentioned correct ?

and in conclusion would your advise be to just move ahead and forget it all
Edward W. Hook M.D.
Edward W. Hook M.D.
37 months ago
No, having exactly the same number in your lab tests if you are below the limit of detection as yours are does not concern me at all.  I urge you to believe your test results.

Yes, I would urge you to move ahead without concerns about HIV. EWH
---