[Question #3974] HIV Window period & Test accuracy despite symptoms
83 months ago
|
Good morning,
Without writing a long story I will describe my concern in timelines in Hope's someone can shed some light.
January 15th - Potential exposure
Unprotected sex with
sex worker (vaginal)
February 27th- Noticed some circular
Rash on penile shaft
February 28th- Alere HIV combo rapid
Test (finger prick)
Result = negative
March 3rd - Developed swollen
Lymph nodes on right
Side of the neck
Largest measuring 2cm
In length by 0.6x0.7cm
Left side of neck:
Largest measuring
7x4x8 MM.
March 4th & 5th - Night sweats two
Nights in a row.
March 4th-9th. - Sharp back pain.
Feeling of fullness
After eating very
Little. Extremely
Fatigue for a week.
March 6th - Full STD panel
- Clhamydia - NEG
- Gonorrhea - NEG
- Syphilis - NEG
- HIV AB/AG - NEG
- Blood drawn from
Vein (sent to lab)
March 12th - CBC w/ Differential
All normal except
The following.
- Lymphs - 19%
- Normal range:22-57%
- Neuts - 74%
- Normal range:36-68%
March 14th - HSV1 Glycoprotein G
Ab IgG.
- Positive 41.60range
March 14th - HSV2 Glycoprot IgG
Ab by Elisa
- Equivocal 0.92range
Questionable range
Would be 0.91-1.09
- 1.10 or greater
Would be considered
Positive.
March 26th - CBC w/ Differential
- All normal even
Neuts and lymphs
- Lymphs - 25%
- Neuts - 64%
March 27th - HIV Ab/Ag - NEG
Blood drawn from
Vein.
- HSV2 Glycoprot IgG
Ab by Elisa
- 0.82 = negative
Ranged dropped from
Last time. ?????
April 17th - HSV2 Glycoprot IgG
Ab by Elisa
- 0.71 = negative
Ranged dropped even
More.
April 18th. - HSV Ab IgG/Igm
Reflex type 1&2
- Results posted
exactly how I got
them.
- HSV 1&2 - 22.40
- HSV 1&2 - 0.61
Doctor annotations: Test for herpes simplex is positive. So you are a carrier of either type 1 or type 2 or possibly both.
July 3rd. - HIV Ab/Ag - NEG
Blood drawn from
Vein.
- Syphilis and Gonorrhea negative
My concern is the lymph nodes I have that were confirmed swollen by my radiologist. I've developed a really
bad dry cough for almost a week now. Sore throat and tonsils look very swollen. This started on July 6th and
it's getter better as of now but still present. I am confused about windows periods as I read and even heard from
my own doctors say 3 months....and others have said 6 months. I've also noticed that I have only been given given the 4th generation test only. I've heard this is only good at 28th days since antigen levels can only be
detected for so long. I am confused on that ??? When would my test results be considered conclusive despite
confirmed symptoms from my doctors. I have not been diagnosed with anything as of today from these symptons. Also tested negative for mono and CMV.
Without writing a long story I will describe my concern in timelines in Hope's someone can shed some light.
January 15th - Potential exposure
sex worker (vaginal)
February 27th- Noticed some circular
Rash on penile shaft
February 28th- Alere HIV combo rapid
Test (finger prick)
Result = negative
March 3rd - Developed swollen
Lymph nodes on right
Side of the neck
Largest measuring 2cm
In length by 0.6x0.7cm
Left side of neck:
Largest measuring
7x4x8 MM.
March 4th & 5th - Night sweats two
Nights in a row.
March 4th-9th. - Sharp back pain.
March 6th - Full STD panel
- Clhamydia - NEG
- Gonorrhea - NEG
- Syphilis - NEG
- HIV AB/AG - NEG
- Blood drawn from
Vein (sent to lab)
March 12th - CBC w/ Differential
All normal except
The following.
- Lymphs - 19%
- Normal range:22-57%
- Neuts - 74%
- Normal range:36-68%
March 14th - HSV1 Glycoprotein G
Ab IgG.
- Positive 41.60range
March 14th - HSV2 Glycoprot IgG
Ab by Elisa
- Equivocal 0.92range
- 1.10 or greater
March 26th - CBC w/ Differential
- All normal even
- Lymphs - 25%
- Neuts - 64%
March 27th - HIV Ab/Ag - NEG
- HSV2 Glycoprot IgG
Ab by Elisa
- 0.82 = negative
Last time. ?????
April 17th - HSV2 Glycoprot IgG
Ab by Elisa
- 0.71 = negative
Ranged dropped even
More.
April 18th. - HSV Ab IgG/Igm
Reflex type 1&2
- Results posted
exactly how I got
them.
- HSV 1&2 - 22.40
- HSV 1&2 - 0.61
Doctor annotations: Test for herpes simplex is positive. So you are a carrier of either type 1 or type 2 or possibly both.
July 3rd. - HIV Ab/Ag - NEG
Blood drawn from
Vein.
- Syphilis and Gonorrhea negative
My concern is the lymph nodes I have that were confirmed swollen by my radiologist. I've developed a really
bad dry cough for almost a week now. Sore throat and tonsils look very swollen. This started on July 6th and
it's getter better as of now but still present. I am confused about windows periods as I read and even heard from
my own doctors say 3 months....and others have said 6 months. I've also noticed that I have only been given given the 4th generation test only. I've heard this is only good at 28th days since antigen levels can only be
detected for so long. I am confused on that ??? When would my test results be considered conclusive despite
confirmed symptoms from my doctors. I have not been diagnosed with anything as of today from these symptons. Also tested negative for mono and CMV.
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H. Hunter Handsfield, MD
83 months ago
|
Welcome back, but sorry you found it necessary.
I reviewed our discussion from a couple of months ago. You're asking more question about the same exposure -- but they were answered that time. As I said then: "The AgAb (4th generation) HIV test is absolutely conclusive any time 6 weeks or more after the last possible exposure, and the results always overrule symptoms (no matter how typical of an acute HIV infection) and exposure history (no matter how high the risk at the time). Your symptoms are not typical for HIV or any STD, and apparently you had a low risk exposure, since you call it "potential". But these things don't matter any way: the HIV test results prove you don't have it." Those facts have not changed.
---Three months is old news for the window period for HIV testing, going back to the earliest (first and second generation) antibody-only tests. The current AgAb test (4th generation) is ALWAYS conclusive by 6 weeks, even though some doctors continue to say 3 months or other times. But if your doctor still wrongly believes 3 month testing is necessary, feel free to do it. If you do, the result will remain negative.
If your symptoms continue or you otherwise remain concerned, discuss further with your doctor. HIV isn't the cause and neither is any other STD. All your symptoms are unrelated to the sexual exposure last January.
I hope these comments are helpful. If anything still isn't clear, please re-read all the details in your previous thread. If still not clear, feel free to let me know.
HHH, MD
83 months ago
|
Good morning Dr. Handsfield,
In length by 0.6x0.7cm
I appreciate your response to my concerns regarding my situation. I only called it a "potential exposure" because I do not the health status of the other person. You confirmed with a reply that it was a high risk after I verified what kind of individual it was. I understand you say that the 4th generation test is conclusive from 6 weeks and beyond from the day of the incident (Regardless of any type of symptoms. I was only simply trying to do what you have wrote on your very last reply on my first question asked. "To secure in the knowledge that I do not have HIV or any other STD's in general". I have expressed my concerns to my primary physician about my lymph nodes and all he can say is that "all we can do is observe and monitor". In your professional opinion Dr, what would you suggest on what I can do in finding out
why are my lymph nodes enlarged. Right Side of the neck
Largest measuring 2cm In length by 0.6x0.7cm
Left side of neck:
Largest measuring
7x4x8 MM.
Largest measuring
7x4x8 MM.
Can it all be coincidence that these symptoms started to occur after my suppose exposure. Was this going to happen anyway?. It's concerning because I was see the
raised bumps on my neck. It keeps reminding me why they can potentially be there.
Thank you Dr. Handsfield
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H. Hunter Handsfield, MD
83 months ago
|
First, self assessment of enlarged lymph nodes is highly unreliable, especially by medically untrained persons. Second, previously inflamed nodes can stay enlarged indefinitely, so past colds, localized infections, etc can cause such bumps that don't mean anything. Third, there are tissue irregularities that can seem abnormal but are not (one of the main reasons self assessment is hard to interpret). Finally, even with true lymph node enlargements, minor, unimportant infections and other problems often are responsible.
Having said that, any potentially enlarged nodes or unexplained lumps that persist more than 2-3 weeks should be professionally evaluated. Some causes are dangerous, e.g. tuberculosis and other infection; and lymphoma or other cancers. The doctor or clinic evaluating you will first determine whether these things are real or important. If so, they will also be in the best position to decide how to diagnose the underlying problem. There are several possible means for doing so.
In any case, from your test results, you know for sure you don't have HIV. But as just suggested, you should see (or continue to work with) your doctor if you are convinced the lumps are real or if you otherwise remain concerned.
That concludes the two follow-up comments and replies included with each question and so ends this thread. This will have to be your last one on these symptoms and your HVI test results. Thank you. But I do hope the two discussions have been helpful.
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