[Question #4324] Question #4314] follow up concern about test validity and drug use.

30 months ago
Hi, 

Follow up on 4314 (Exposures three years ago, tested 4th gen negative a year ago, oraquick negative 3 days ago) So following advice I took a 4th gen HIV test and it is non reactive. Can I be sure that this excludes the exposures happened three years ago? 

2.) The night before the test I have smoked marijuana, could that in anyway produce false results the next day? 
Edward W. Hook M.D.
Edward W. Hook M.D.
30 months ago
Welcome back to the Forum although I must say, I'm dismayed that you continue to be concerned.  As I indicated earlier, your results were conclusive (or definitive if you prefer that word) before and your more recent results only serve to confirm what we already know.  You did not get HIV from the exposures in China that you described.  I urge you to accept this and move forward.  YOU DID NOT GET HIV FROM THE EXPOSURES YOU DESCRIBED.

2.  The is NO affect of Marijuana on the performance of HIV test results.  Once again, please believe your test results.  There is no reason for continued concern and no reason for doubt.  EWH
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30 months ago
Thanks for the reply doctor. With 2 negative 4th gen HIV test and one oraquick rapid test I think I can be sure that I am not infected with HIV. 
I do have reservations on marijuana effect on the testing itself. Do you know why marijuana or other recreational drugs cannot influence hiv tests and antibody productions? 
Edward W. Hook M.D.
Edward W. Hook M.D.
30 months ago
We receive many questions of this sort.  A better question is why should marijuana influence antibody production.  Scientists thoroughly study both the immunological process of antibody production and new tests to make sure that alter or interfere with test production when new tests are in development.  There have been no studies that suggest that marijuana effects immunity or the biochemistry of test performance.  As you I'm sure know, marijuana smoking is common yet there are no data to suggest that it effects detection of HIV in any way.  Finally, even if marijuana smoking did effect immunity, if one were to become infected the virus, and therefore its antigen which is also looked for in the 4th generation tests, would be detected.

I urge you to believe your test results.  EWH
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