[Question #4378] Mycoplasma Genitalium test window

30 months ago
What is the testing window for Mycoplasma Genitalium?  Unprotected sex with a woman on Septermber 14.  Urine test 17 days later on October 1.  Tested negative for Chlamydia, Gonnorea, Trich, Ureplasma and Mycoplasma.  Today, experiencing pain during urination, but no discharge.  I'm worried about MG because I tested positive before.  Is this just anxiety?
H. Hunter Handsfield, MD
H. Hunter Handsfield, MD
30 months ago
Welcome back to the forum. I reviewed your discussion with Dr. Hook 10 months ago. He recommended retesting for M. genitalium at that time. Did you do that? What was the result?

Also please provide more detail about your test results 2 weeks ago. Does "Mycoplasma" mean M gentalium? There are other genital mycplasmas that are entirely normal in the genital tract, but a specific test is required to detect M genitalium. If that was done, the result should be considered conclusive. There have been no studies of the testing window, but almost certainly a test done 2+ weeks after exposure would detect any and all infections.

As for painful urination, this is rarely due to any urethral infection or STD, unless there also is abnormal discharge. In other words, without discharge you can be confident it isn't due to M genitalium. If it continues, or if you also develop urgent urination or discharge, see a doctor or clinic for further evaluation. But if it goes away over the next day or two, you needn't worry about it.

I'll be happy to provide a bit more information if you can clarify the test(s) done. In the meantime, I hope this information is helpful.

HHH, MD
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30 months ago
Thank you doctor.  Sorry I did not provide enough detail in my original post.  This was a new test different from the one 10 months ago.  I did not return for a retest at that time because I no longer experienced any symptoms.  

For this recent test I specifically asked the doctor to test for MG because of my prior experience with it, and it was something he said they don't normally test for. Yes, I was having some painful urination and an urgency to pee, but no discharge.  the symptoms are not as strong today and I feel a little better.  
H. Hunter Handsfield, MD
H. Hunter Handsfield, MD
30 months ago
Given your previous documented M genitalium infection -- and the fact that your treatment then did not include moxifloxacin (at least not that I recall), which is the drug of choice for MG -- if your symptoms continue, it would be reasonable for you to be retested for it. (Presence or absence of symptoms may not be predictive of infection. Many MG infections are entirely asymptomatic.) Most likely you no longer have it, but testing is the only way to know for sure.

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