[Question #4521] Lymph node and RNA question
81 months ago
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Dr.s,
It's been 3 months since my last question so I hope I can ask again. Frankly, I've found you two both more understanding and reliable than anyone I've met with in person, MD's and therapists alike. I have been doing much better overall, but I got in a dark place about lymph nodes and had a few more questions I hope help me and others.
1. Knowing there is nothing specific about a lymph node with HIV, are their any signs that a lymph node could be related to HIV? What I mean is that I felt my first posterior cervical node 30 days after my exposure by accident in the shower. This led to the dreaded 'self examination' where I found at least one more on the same side (right) and one other in a similar location on the other side of my neck. Eventually found another few in the front left, anterior later on. Every single dr who examined them said they were normal and of no concern. Some didn't even feel them until I directed their hands to them. I eventually had a U/S done of the 2 on the right, the bigger one came in just under a cm and is long like a worm. The other smaller and like a pea. I read Dr. HH describe HIV nodes as a marble, curious if there was anything else to describe it. The dr. who examined the U/S first told me that this was way too early for HIV lymph nodes (incorrect) but in any case these looked very healthy to her. If they were caused by HIV, would anyone describe them as health on a U/S? Also, I'm exactly a year from the exposure and the nodes are all unchanged. Would HIV nodes last that long? (11 months)
2. I took a quest RNA/PCR Quant test 26 days post exposure down to 20 copies. Undetectable. I then took a 95 day panel at labcorp and was all neg. However, I found out about potential biotin interference with immunoassays (link below). I don't want to get into the weeds about biotin interference with you. But I'm curious to see if you cancelled that out, would my RNA/PCR test at 26 days be conclusive on it's own? Thank you.
https://www.healthcare.uiowa.edu/path_handbook/Appendix/Chem/BiotinImmunoassayTables.pdf
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H. Hunter Handsfield, MD
81 months ago
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