[Question #4585] Follow up on [Question #4243] Single act 16 years ago

26 months ago
HI DrHHH, i've subsequently taken 2 home tests (Biosure) here in the UK, they are CE Marked and state a 99.7% accuracy. Both have been negative. But I notice they are afinger prick blood 2nd generation. your statement on a previous reply to me has concerned me that i cant take this as conclusive as they potentially miss some infections?  here is a link to the BioSure just in case you are not familiar with it.

Can I close this chapter and conclude I am negative 16 years after the exposure?

https://hivselftest.co.uk/


26 months ago
Also if i was an elite controller would it affect the results of this test?
H. Hunter Handsfield, MD
H. Hunter Handsfield, MD
26 months ago
Welcome back to the forum, but sorry you found it necessary. However, I'm very glad you finally were tested.

Your test results prove for sure you were not infected -- Congratulations! That they are officially certified as "only" 99.7% efficacy is at least partly an artifact of how such tests are tested for accuracy and the approval policies of government agencies. There are almost no tests in the world for any disease that are any more accurate than this, and this is 100% for all practial purposes. In your other two threads, Dr. Hook and I discussed all the other reasons you can be sure you don't have HIV. Bewteen those facts and the test result, you now have 100% proof you do not have HIV. And no, "elite controllers" all have normal (positive) HIV test results.

I hope thiis allows you to put this chapter in your life beyind you and move on with no further worry about it. And for goodness' sake, no more internet searching about this, including about HIV test performance.

Best wishes--  HHH, MD
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26 months ago
Thanks Doc for your valuable service. You've been a great help 
26 months ago
Hi doctor just to close this off. Are you happy this was a 2nd generation test? Presuming you are considering it was 16 years post exposure. 

Out of interest what is the difference between the different generations? 

Many thanks 
H. Hunter Handsfield, MD
H. Hunter Handsfield, MD
26 months ago
Yes, 2nd gen is fine any time more than 12 weeks after the last possible exposure. The main difference between 2nd and 3rd gen it more sensitivity, i.e. 3rd detects lower levels of HIV antibody and therefore is conclusive sooner, generally 6-8 weeks. With 4th gen, the antibody test is identical to 3rd gen, but the test also includes a test for HIV antigen, i.e. the virus itself in addition to antibody. 4th gen is almost always positive by 4 weeks, although in rare cases it can take 6 weeks, which is our general advice on this forum.

After 12 weeks there is no difference between them in detection of infected persons.

That concludes the two follow-ups and replies that come with each question, and so ends this thread. I hope the discussion has been helpful. Best wishes.

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