[Question #4900] Risk of HVS1 outbreak between two infected partners

27 months ago

My wife has a permanently compromised immune system due to a previous chemotherapy treatment for SLE Lupus. She has tested positive to HSV-1 through a swab test of vaginal and oral lesions (both sets tested HSV-1 positive and HSV-2 negative) and she is currently suffering from her primary outbreak. I am a male and, though I have not tested positive, I had pain urinating over the past week and suspect that it was due to a herpes lesion in my urethra. We believe our exposure was approximately 2 weeks ago (from new partners).

Our question: If we are both HSV-1 positive, considering her compromised immune system and that she will be on a daily suppression therapy, will unprotected sex between us increase the risk of her outbreaking, assuming neither of us are exhibiting symptoms at that time and if so, would me being on the daily suppression therapy reduce her risk of outbreak from unprotected sex between us?

Terri Warren, RN, Nurse Practitioner
Terri Warren, RN, Nurse Practitioner
27 months ago
No.  IF you are both infected with HSV 1, there is no problem with unprotected sex between the two of you.  it will not cause an outbreak to happen. 
Is that what you are asking?

Terri
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27 months ago
Thank you Terri; yes, you answered our question for the most part; however, you gave us pause with your answer because you specified "...infected genitally..." so for clarification please, is there a scenario of unprotected sex between the two of us (oral sex, mutual masturbation, etc.) that may cause or encourage an outbreak to happen...again assuming neither of us are exhibiting symptoms (orally or genitally) at the time? 

Thank you.
Terri Warren, RN, Nurse Practitioner
Terri Warren, RN, Nurse Practitioner
27 months ago
Sorry, that was an error on my part. It should have read just "infected with HSV 1, regardless of location"

Terri
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