[Question #5106] Following Up Again

25 months ago
Dr HHH,

This is following up to #6201. Despite your reccomendation of no testing I went ahead and got a rapid RNA PRC test 10.5 days after the event.  It was negative.  Today (3 months later) I experienced some neurapathy type tingling in hand and foot.  I know u were clear this was a zero risk situation and was wondering your thoughts about this and the fact I have a negative on the rna.  I understand you dont consider RNA to be 100% but could use the reassurance that this a non event driven by anxiety.   Thank you
Edward W. Hook M.D.
Edward W. Hook M.D.
25 months ago
Welcome back to the Forum.  On this occasion I happened to pick up your new question and will be answering today.  To prepare to answer your questions, I reviewed your two earlier interactions with Dr. Handsfield and agree with all that he said- the encounter you have describes and like Dr. Handsfield, I see no medical reason for testing.  Hopefully, the negative test results that you received will reduce your concerns regarding possible infection.  

The majority of RNA PCR tests will be positive in most persons who have just acquired HIV by 8 days following exposure.  Virtually all PCR tests will be positive by day 14 

Believe your test results, they reinforce our confident statements that you did not acquire HIV from the exposure you described.  EWH
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25 months ago
Thank you Dr Hook.  Sometimes the OCD/Anxiety can get the best of me.  So, done with behind me no way I could have contracted HIV.  Correct?
Edward W. Hook M.D.
Edward W. Hook M.D.
25 months ago
Correct. A no risk exposure and data which provide strong evidence to prove, in fact, that you were not.  EWH---
24 months ago
Thanks Dr Hook.  Appreciate your response here.   Sorry to have you be a therapist here. 
24 months ago
Sorry Dr Hook, figured this thread is still open so one more question if I may.   It would appear the only thing not short of 100% is a 4th Gen antibody test.  My concern there is a false positive.   Obviously I took that risk with RNA PCR but would not want to have that happen.  Do labs retest the same same sample if a positive comes up to confirm it is not false with the 4th gen and avoid the wrong result?  Thanks 
Edward W. Hook M.D.
Edward W. Hook M.D.
24 months ago
Good questions.  typically PCR tests are performed on different specimens (plasma) than 4th generation, combination HIV antigen/antibody tests and once tests are done in most laboratories, if further, reflex testing is not part of the protocol, any excess specimen remaining after testing is discarded.  I would not worry about false positive test however with the combination tests, they are far less common than FPs are with p=PCR based tests.

I hope this helps.  In my opinion however, based on all that you have said in this and prior posts, I see no medical or scientific reason for additional testing. EWH
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24 months ago
Thanks Dr H, especially for the last paragraph!
24 months ago
Did an ora quick test as well after 3 months.  This was negative.   
Edward W. Hook M.D.
Edward W. Hook M.D.
24 months ago
Please believe this response and do your best to move forward.  It's time!

As per Forum guidelines this thread will now be closed.  You have received more than the standard 3 responses.  Take care. EWH
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