[Question #5135] Herpes IGG Positive Advice

24 months ago
Would really appreciate a quick response. My doctor is out of office today so no one could do anything other than give me results. I won’t see him until Tuesday and I’m not sure I’ll be able to sleep until I get some kind of explaination.

My IGG score for HSV1 was 34 (I was told 0-.9 is typical). HSV2 IGG along with HSV1 IGM and HSV2 IGM were all negative. Tests were done at 10.5 days after exposure. Does this mean I was recently infected with HSV1? Is it possible this is from a long ago infection? Is it possible it’s not actually HSV1 and it’s HSV2?

I was in a foreign country and possibly drugged about 14 days ago. When I kind of came to there was a condom in use but things were happening that I wasn’t OK with. I believe brief oral and vaginal sex. Since then I’ve had all the tingles and feels to the point fungus was suspected but not proven. It was almost a tickle some days. Now I have Urethritis symptoms just towards the tip. For a while it made me think I had to pee but it didn’t hurt when I peed. I’m on an anti fungal/steroid cream for the past 48 hours. Not sure that it’s helped much. No sores in other places as far as I can tell and while there was pink irritation, no sores there. 

Desperate for some insight here. I really appreciate any and all help!
Terri Warren, RN, Nurse Practitioner
Terri Warren, RN, Nurse Practitioner
24 months ago
It is certainly possible that you have been infected for a very long time or it could be more recent.  But with an IgG of 34 for HSV 1, this almost certainly was not from something that happened 14 days ago.  You can put that worry aside.  The soonest I have seen someone become positive is 10 days out and that index value was 1.1.  Have you ever in your life had a cold sore on your lip or in your nose? If yes, then that's where the antibody is coming from.

Terri
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24 months ago
Thanks for the quick reply! Should I be relieved that at 10.5 days I was negative for IGM? My understanding is that would be the only indicator at this point of a recent infection. It’s been a long and stressful ~2 weeks. PEP wouldn’t fight the herpes virus as well, would it?
Terri Warren, RN, Nurse Practitioner
Terri Warren, RN, Nurse Practitioner
24 months ago
No, the negative IgM isn't all that useful.  People have it with new infection and recurrent disease so it's difficult to sort out what a negative truly means.  PEP will not fight the herpes virus, no, and you have a very well established HSV 1 infection now so any attempt to do anything about HSV 1 will not do anything.

Terri
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