[Question #5178] HSV testing and exposure

24 months ago
Hi 
I kissed a man positive on his Igg for HSV2 and HSV 1.  I have hsv1 as well so my fear is of his HSV2. On the same occasion (on January 11th) of the kiss he did bite my lip, and I bled. After this, I was annoyed at the fact that he bit me, so I pushed him away and I stopped kissing him. 2 weeks later he found out about his status. His first positive was low @ 1.25 on the HSV2 Igg. This is a low positive so I encouraged him to take another hsv 2 igg test a couple weeks later. It came back positive again with a higher level of 1.46. I know oral transmission of HSV2 is low, but I am still a nervous wreck because I didn’t just kiss him but I don’t know how the bite could have exposed me more. We have never had any oral, genital, or vaginal sex. No sexual contact at all, besides the kiss.  He sent blood for a Western blot and is currently pending results. I’ve been feeling buzzing or twitching feeling on my skin lately. On my scalp, legs, hands, and face - but I absolutely freak out when I feel that buzzing/ sometimes twitching on my lips. Felt the buzzing since mid February(about 4-5 weeks post exposure). Happens frequently, on and off since then. I took an HSV 2 IGM and IGG 6 weeks after most recent exposure (the kiss/bite) and both returned negative. Took another HSV 2 igg test 2 weeks after that because of the buzzing feeling on my lips(8 weeks post exposure). That came back negative as well. These two tests were taken 2 and 4 weeks after the buzzing feeling on my face and lips was first felt. That still persists till this day. No sores noticed, have seen a pimple or two that cleared up in few pain with no pain, ulceration, or fluid.  But I do know that these things can sometimes be minor, especially since I already have HSV1. My question to you is, does this sound like I have acquired HSV 2 orally, but the blood test can not detect it yet? And at what point can I be certain I have not contracted it by blood testing after 16 weeks or after 6 months have elapsed?   
Terri Warren, RN, Nurse Practitioner
Terri Warren, RN, Nurse Practitioner
24 months ago
His index value 1.46 has an 85% change of being a FALSE POSITIVE.  he needs a different confirmatory test, like the western blot, which is good that he has ordered.  He is likely not infected.
And if he was infected, you did not get HSV 2 from kissing him or the bite.  That's just not how this works.  HSV 2 oral infection is uncommon and when present, is shed on just a few days per year.  I think the buzzing you are feeling has nothing at all to do with herpes.  If you are still worried, you can do a final IgG test at 12 weeks or a western blot

Terri
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24 months ago
Thanks Terri,
My worry, is that something may pop up later in my life. I have seen several situations even on this forum where people have tested at one time and been negative and without any new partners test positive months later.  In your experience what is the latest you’ve seen a false negative finally show positive on a person with HSV2? And the western blot is 100% effective @ 12 weeks post exposure? 
Terri Warren, RN, Nurse Practitioner
Terri Warren, RN, Nurse Practitioner
24 months ago
Some people simply do not wait long enough from an encounter to have an accurate test.  And some people have low positives that may be false positives.  The western blot picks up >99% of HSV 2 infections at 12 weeks post exposure. 
It would be a kind thing to do to tell this person to get their HSV 2 result confirmed with a blot or Biokit

Terri
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24 months ago
Thanks Terri, 
Did you mean >99%?
And in your experience what’s the longest you have seen before HSV2 appear negative before it apppeared on an IGG test? 
24 months ago
Sorry I mean to say : 
And in your experience what’s the longest time period you have seen before HSV2 apppeared positive on an IGG test?
Terri Warren, RN, Nurse Practitioner
Terri Warren, RN, Nurse Practitioner
24 months ago
I have seen 10 people who have positive swab tests from obvious lesions who have never become positive on the blot.  Other than those people I have not seen it take longer than about 12 weeks UNLESS someone is taking daily antiviral medicine and then I have seen it take more than 18 months, if antiviral therapy is taken daily.

Terri
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