[Question #5514] Follow-Up to [Question #5436] Conclusive Syphilis Testing

23 months ago
Hey Docs - sorry another anxiety fueled question which I know you love! In my previous question I had a negative 8 week RPR done by LabCorp. My anxiety unfortunately got the best of me and I went back for a 10 week RPR which was also negative from LabCorp because I was afraid of the prozone effect and whether I had gotten a false negative. I figured if I had another negative RPR both of them couldn’t possibly be false negatives! Is there any reason to have another RPR test after 12 weeks or am I in the clear (with negative RPR at 8 & 10 weeks)?  Any reason something would show up later or something these RPR tests did not catch?

Thanks again for all you do for everyone on this site and around the world. 
H. Hunter Handsfield, MD
H. Hunter Handsfield, MD
23 months ago
Welcome back, but I don't really understand why you found it necessary. This was answered conclusively by Dr. Hook in your other thread. You could not have caught syphilis from the exposure described and your previous test result was conclusive. There is no chance that either the previous result or the more recent one is falsely negative.

As I think you understnad, this is your OCD speaking. It is not normal to remain so concerned after the reasoned, science based reassurance you have had -- perhaps from your own docot(s) as well as this forum. If you're in counseling, I suggest you discuss your fears with your therapist. If not, perhaps it's time to find one. I suggest it from compassion, not criticism.

HHH, MD
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H. Hunter Handsfield, MD
H. Hunter Handsfield, MD
23 months ago
There was a typo, now corrected. Last two words of paragraph 1 now are correct:  "falsely negative".---
22 months ago
Thanks Dr HHH.  I got tested with qualitative RPR which looks like it reflexes to a quantitative RPR. Can I assume the qualitative RPR is perfectly fine since my test was non reactive anyways?
H. Hunter Handsfield, MD
H. Hunter Handsfield, MD
22 months ago
A negative qualitative RPR is conclusive, in which case the quantitative test is not done and unnecessary. In fact, quant cannot even be done unless qual is positive.)---
22 months ago
One more to close this out. Have you ever seen a negative RPR at 8 or 10 weeks turn positive later? Any reason to test further?  Have a great 4th of July!
H. Hunter Handsfield, MD
H. Hunter Handsfield, MD
22 months ago
No, I've never seen this. It can't happen!

Please accept the reasoned, science-nased inforation and advice you have had and nmove on without worry. And please no more questions on this topic. Thanks.
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