[Question #5689] In Correspondence to Question #5641] HSV-1 Genital Herpes

21 months ago
Hi Terri,

You mentioned genital HSV-1 sheds 18 days (~5%) in an earlier message but in another response you mentioned 55 days per year.  Can you please confirm which is correct.

If someone does not have recurrent cold sores how often is the virus shed?  And with genital HSV-1, if one does not have any outbreaks after the initial outbreak what is the shed rate?  Thank you!
Terri Warren, RN, Nurse Practitioner
Terri Warren, RN, Nurse Practitioner
21 months ago
I corrected that to 5% of days - that is for genital HSV 1
We do not have data on how frequently someone with oral infection but no recurrent cold sores are shed.
We only have general information about shedding of HSV 1, not down to the specific detail that you are asking about someone with no outbreaks and shedding rate.


Terri
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21 months ago
Thank you.  Regarding taking Valtrex daily medication for HSV-2, what is the % possibilty of still infecting a negative partner?  I think you said you do not have any specific data taking Valtrex and genital HSV-1.
21 months ago
Is there any estimated percentage split on the overall annual shed rate through asymptomatic shedding vs an outbreak?  I assume a majority of the high chance of infection would be during an outbreak.  
Terri Warren, RN, Nurse Practitioner
Terri Warren, RN, Nurse Practitioner
21 months ago
So daily Valtrex reduces transmission by about half - it starts at about 10% IF having sex twice per week without a condom and with no sores present. 
I just attended a meeting where there was a paper on shedding of HSV 1. Within the first 6 months, it appears to be about 3.8% and after a couple of  years, it dropped to 1.8% of days.  I would guess it's about evenly split between symptomatic and asymptomatic. 

Terri
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