[Question #5745] Testing Results

20 months ago
Hello
I had an HIV RNA test performed at 12 days that came back negative.  Also, I had a Herpes Elisa igG test performed at  21 days  with negative results.  These test were performed following unprotected oral ( im a male received from female) , followed by kissing and two episodes of  protected vaginal sex.  Are both of these results conclusive enough to not warrant additional testing?  Also , your site is very helpful; is there an organization you recommend to make donations to?  Thanks 
Edward W. Hook M.D.
Edward W. Hook M.D.
20 months ago
Welcome to the Forum.  I'll do my best to help.  The encounter you describe was relatively low risk for most STIs.  Most women do not have STIs, most exposures to infected partners do not result in infection, and condoms are highly effective for STI prevention.

HIV is not acquired from receipt of oral sex or kissing and condoms are highly effective for HIV prevention.  Had you asked if I thought you needed testing for HIV, I would have said no.  You chose to test.  Most experts feel that an HIV RNA test any time more than 11 days after exposure are highly reliable but would still suggest follow-up using a 4th generation  HIV antigen/antibody test at 6 weeks just in case.  In your specific case, given the no risk nature of your exposure, I see no reason for further testing.

We do not recommend use of the HSV ELISA for diagnosis of infection.  It is typically sufficient to wait for about 10 days after exposure and if you have not developed lesions suggestive of herpes, to move forward without concern.  The HSV blood test has a high rate of false positive tests (glad that did not occur for you) and is not really fully conclusive until about 4-6 months after an exposure.  Personally, we would not recommend further testing for HSV following the exposure you describe as well.

I hope this information is helpful.  Should you wish to make an additional donation, we would suggest the sponsor of this site, The American Sexual Health Association (ASHA) a non-profit which does much good advocacy in the name so sexual health.  EWH
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20 months ago
Thank you.  On a separate issue, do you know of any conditions that cause lip swelling?  My lower lip seems to swell randomly and causes my front teeth to rub it.  It comes and goes , but seems to happen more at night, usually as I sleep.  No sores or anything like that , and started about 2-3 weeks ago.  It’s very random.  Thank you 
Edward W. Hook M.D.
Edward W. Hook M.D.
20 months ago
I'm pleased my earlier responses were helpful to you.  I am at a loss to explain your randomly episodic, nocturnal ip swelling.  My suggestions would be to keep a written record- when did it occur, how did not become aware of it, was it following some activity or ingestion, etc. to look for a pattern.  After recording this for several episodes, discuss it with your regualr doctor.  EWH---
20 months ago
Thank you. 
20 months ago
I know there is a limit on questions , I can pay again if needed.  I read my hsv1 test result incorrectly.  It’s says it was positive at 1.36.  I tested last year and was negative and only had the encounter  I mentioned above.  No symptoms of anything.   Could I have gotten it from this one incident or could this be s false positive.  Thanks
Edward W. Hook M.D.
Edward W. Hook M.D.
20 months ago
Your blood test is in the range where many such results are falsely positive.  Your experience is just the reason we recommend against these tests in situations like yours.  I doubt that this is HSV.  If you desire to evaluate this further, you can post a herpes related question on this site for Terri Warren who answers our questions on HSV or seek a confirmatory Western blot test from the University of Washington- this is the gold standard test for HSV antibodies and is done only at the University of Washington.  

This will complete this thread.  I really doubt that you acquired HSV.  EWH
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