[Question #6604] Possible to have no viral load and no antibodies after 1 year?

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66 months ago
Quick question Doctor! I have read stories of people having undetectable viral loads without being on meds. Is this due to a strong antibody production? 

I know its known as rare, but can someone have a undetectable viral load and no detectable antibodies or if that person didn't have antibodies would their viral load be sky high (because nothing would be able to stop the virus from multiplying?) lets safe after 1 year? 

Also the tests I took my tests on were 1) abbott architect 2) hiv pcr rna cobas/taqman. Are these both good? 

Thanks!
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Edward W. Hook M.D.
66 months ago

Welcome to the Forum.  I'll be glad to comment.  your reading is correct.  There are a very small group (a small fraction of 1%) of persons with HIV who are, for reasons that are not well understood, able to control their HIV infection so that it does not progress despite not taking anti-HIV.  Even these people however have positive tests for HIV and detectable HIV viral loads.  Thus, if your tests are negative (and they are), you can be completely confident that you do not have HIV.  Believe your test results- both of the tests you took are superb tests which would not miss an infection if you were HIV infected.

I hope that this comment is helpful. EWH

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66 months ago
Thanks! I have a 3 part question if you don't mind. 1) If someone didn't have antibodies would their viral load be skyrocketed due to nothing "stopping the virus?" 2) Once antibodies are formed/"turned on" can anything "delete/destroy" them  and make them undetectable 3) Ive read a lot that most experts don't base HIV on symptoms, why is this? Since ive had a possible exposure ive noticed the following : low T (proven by blood work, only 34 years old) change in stools (softer), seb dermatitis. Don't you think thats kinda a weird  coincidence? Even those from my last thread you can see many negative/not detected/non-reactive tests up to around 16 months....
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Edward W. Hook M.D.
66 months ago


1.  Yes.  The antibody response to HIV helps to control the viral load,.  Without antibodies the viral load would be high.

2.  No, once a person has HIV and is making antibodies, the remain antibody positive.

3.  I think you are over thinking this and need to stop worrying.  The problems you note are coincidence.  Your multiple negative HIV tests prove that you are not infected. 

Please do not go down this rabbit hole.  There is no reason to do so.  EWH

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66 months ago
Thanks Doctor ! I think sometimes I need the reassurance. Im a pretty healthy guy (workout, eat pretty decent etc) but always think I might be one of "rare" guys with a delayed antibody response, or somehow have no detectable viral load. Its just the weird way my body is reacting (mainly low T) that always makes me second guess myself. Thank you for everything!