[Question #6612] HPV and IVF

15 months ago
I was recently diagnosed with HPV on my cervix after having been tested for the first time in my life. I have been with the same partner for 10 years, a heavy smoker who likely transmitted the virus to me. We stopped using condoms 2 years ago to try to conceive and ended up doing 6 IVF egg collections last year, while taking prednisolone at times.
-Can HPV impact my fertility treatment and how?
-Can IVF worsen my HPV or make it persistent?
-Can my partner and I keep on reinfecting each other with HPV?
-How likely is this HPV going to be persistent? It looks like I either had it for 10 years or it was reactivated recently
Edward W. Hook M.D.
Edward W. Hook M.D.
15 months ago

Welcome to the Forum  Thanks for your questions.  I'll be glad to comment.  When persons first find that they have HOV there are three main questions that are asked.  Who give this to me, how long have I had it, and what can you do about it.  There are almost never good answers to the 1rst two questions since  over half of women have gotten HPV within a year of having started to have intercourse.  what to do about the 3rd question has a number of answers and is probably best answered by your OB/GYN particularly given that you are in the midst of IVF treatment.  I can assure you however that HPV is not known to have  any meaningful impact on the health of babies born to infected mothers and that the infection is not transmitted at birth in well over 99% of deliveries.  Your prior prednisolone treatments, depending on timing, duration and dose MAY have impacted your likelihood of reactivating HPV but again, this is really something to discuss with your OB/GYN if you have not already.  If you have, what did she/he say?  The bottom line however is that your HPV diagnosis should not cause problems with your pregnancy.

In response to your specific questions:

-Can HPV impact my fertility treatment and how?
It should not.

-Can IVF worsen my HPV or make it persistent?
Some of the hormones take during the IVF process might impact the detection (tendency towards persistence) of HPV.  Again, best to discuss the particulars with your doctor.

-Can my partner and I keep on reinfecting each other with HPV?
No.

-How likely is this HPV going to be persistent? It looks like I either had it for 10 years or it was reactivated recently.
As noted above, it is difficult to say how long you have had HPV or whether it will persist. During pregnancy HPV can become more apparent and then regress following delivery.

I hope these responses are some small help.  Your situation with IVF is a bit specialized and is really something to work through with your OB/GYN.  EWH
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