[Question #6646] When test after PEP ?
14 months ago
Edward W. Hook M.D.
14 months ago
Welcome to the Forum. Thanks for your questions. I happened to be on the Forum when your questions arrived so you are receiving a reply more rapidly than is often the case. Responses to any follow-up questions may take longer.
Following an exposure to a partner known to be infected with HIV the risk for acquiring HIV is never higher than 1% and, depending on the type of exposure, may be considerably less. PEP reduces the risk for acquiring infection even more and is thought to reduce the risk for HIV infection, even more- about 80% in many studies as long as it is started within 72 hours of the exposure. The sooner PEP is started the more effective PEP is. In your case I presume that you do not know whether your partner had HIV or not. You can be sure that there is a more than 99% chance that you did NOT get HIV as a result of your broken condom. With this background, I can assure you that your test results definitely prove that you did not get HIV from the exposure that you mention. More detail:
1. The value of most of your 3rd generation, antibody only tests is questionable. Even without PEP these results would not be definitive until at least 8 weeks (56 days) after exposure and with PEP that period becomes longer.
2. On the other hand, your 4th generation tests do prove that you were not infected. For persons on PEP results are considered definitive 3 months (120 days) after the exposure and at 8 weeks following completion of PEP. This your results from 90 days are highly suggestive and the results from 130 days are conclusive.
3. Your 120 day results, particularly when considered with your other test results are also conclusive
Thus, in answer to your specific questions: