[Question #6777] Will combo test still be negative at 12 week mark ?

12 months ago
Hi my last exposure condomless sex with a csw was in 22/01/20suddenly I have got a sore throat within two weeks of exposure with a white tongue and swollen circumvamate along side a dry mouth ,and my stomache is always growling and diarhoea I had  sex with my wife from the 30/01/20  till the 7/02/20 now I’m scared I have passed it on to her  she has has had a combo approx 7 weeks result was 0.08,                                                     My most recent tests are.                                                 1/hiv combo alinity s Reagant 8 weeks past last exposure result 0.09.                                               2/hiv pcr quantative at 6 weeks 5 days past exposure result not detected.                                     3/hiv qualitative Cephied genexpert 3 weeks 5 days past exposure  negative                                   I4/ alere determine rapid combo prick test 6 weeks 5 days past exposure  negative                   In Pakistan only pcr test available is the pcr quantative if I get that done again should that be ok the cut it is  40 copies also , how many copies would they be by now and have u ever seen a combo turn positive at the 3 month mark , I’m worried because of my throat can’t be a coincidence ???
Edward W. Hook M.D.
Edward W. Hook M.D.
12 months ago
this is a repetitive question which was answered just two days ago.  Repeating your question will not change the responses you receive.  Indeed, your test results do PROVE that your symptoms are a coincidence and that you DO NOT have HIV.  There are many, many causes of sore throat, white tongue and diarrhea.  If you had HIV, your tests would have been positive.  I once again suggest that you look for other causes of your symptoms.  EWH
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12 months ago
Would they always be hiv rna in the blood even after 3 months if exposure ? , reason I ask is because I had two previous exposures before this , I’m thinking of doing another hiv quantative  and qualitative  test , how many copies would they be of rna in these tests at 8-9 weeks past exposure ? , also have u ever seen anybody come up positive after 7 weeks combo negative , also I’ve done a complete blood count where would they be markers for worry in that report ?
Edward W. Hook M.D.
Edward W. Hook M.D.
12 months ago
Sigh.  You really need to get over the idea that you have HIV.  You do not !!!   When persons have HIV, they have tens of thousands of viral particles in every drop of blood from then on, for the rest of their lives unless they are treated.  You need to believe your test results; you are not infected.  Further testing related to your past exposures is a complete an absolute waste of time, energy, and resources.  EWH---
12 months ago
I’m sorry to bug u but I’m anxious at this test becoming positive at 3 months mark , so basically if I were to do the quantative tets whenever from date of exposure your telling me there would be tens of thousands of copies ? Because I read it can fall below the level of detection I.e 40 copies of rna , at 8 weeks since exposure would my white blood cells drop ? Have u ever came across anybody who becomes infected at 3 month mark prior to negative ,combo tests ?
Edward W. Hook M.D.
Edward W. Hook M.D.
12 months ago
As you know. We provide up to three responses each question. This will be my third and final response. Your questions are repetitive. Either you are not reading my responses or not believing them. You have repeatedly proven that you do not have HIV. You have done this using more than one type of test. All of your results with each of your tests is conclusive and should be believed..

Your anxiety is misplaced. You do not have HIV.

Your repeat of my response is correct. If you had acquired HIV and were untreated your quantitative or qualitative RNA PCR test would be strongly positive with tens of thousands of viral particles in each drop of blood. This test would remain positive throughout the duration of disease unless you were treated.  For the diagnosis of HIV the test limit of detection is completely irrelevant. The quantitative PCR tests are important for following response to treatment, not for diagnosis. We use quantitative test to make sure that the amount of virus in the blood in treated patients is declining. Once again your results are conclusive.

Likewise, testing for your white blood cells is silly and irrelevant. White blood cells vary dramatically on a daily basis and can rise or fall in response to a huge number of different causes. Just as further testing for HIV is a waste of time, money, and energy, testing for white blood cells has no relevance to whether or not you have HIV which you do not.

This will conclude this thread. There should be no need for you to return to the forum with repetitive, anxiety-driven questions. Should you return with repetitive and similar questions of the sort you have asked, your question may be closed or deleted without a response and without return of your posting fee. I hope you understand. Take care. EWH
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