[Question #7017] Syphillis testing
60 months ago
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Edward W. Hook M.D.
60 months ago
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Welcome to our Forum and thanks for your questions. I'll be glad to clear things up. Let me start by assuring you that your test results show that you did not acquire syphilis through your exposure to this partner. I'll now provide some additional explanation.
1. Even if your partner had syphilis at the time of your encounters, syphilis is not transmitted at 100% of exposures, instead only being transmitted about 1/3 of the time.
2. Your test results reflect recent changes in the way syphilis testing is done. The newer tested for syphilis IgG/IgM unfortunately occasionally give falsely positive results. The way that we know that your tests were falsely positive is because, as I read your post, the lab then went on to do two additional tests, the RPR and TPPA which are unrelated to your first test. If you had acquired syphilis all three tests would be positive. When only one test is positive, this indicates that it is the test that is wrong (falsely positive)
Thus you can be confident that you did not acquire syphilis from this exposure. FYI, we cannot say whether or not future tests will be falsely postiive or not. Sometimes the false positive tests are transiet, sometimes they are persistent.
I hope this clariifies things. If you have additional questions or if any of this is unclear, please use your up to tow follow-up questions for clarification. EWH
60 months ago
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Edward W. Hook M.D.
60 months ago
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60 months ago
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![]() |
Edward W. Hook M.D.
60 months ago
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60 months ago
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![]() |
Edward W. Hook M.D.
60 months ago
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60 months ago
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![]() |
Edward W. Hook M.D.
60 months ago
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Thanks for the follow-up. I know this is reassuring. You are in the clear. Just beware that in the future, if screened again with an IgM/IgG test, you may once again have a false positive test.
Two years is too soon for this to have progressed to late latent infection and for a previously positive test to have become negative. Furthermore, the other syphilis test you had, the TPPA, would have been positive if this were late latent infection. Be confident that you do not have syphilis.
With this, as per Forum guidelines, this thread will now be closed. Take care. Stay safe. EWH
60 months ago
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Edward W. Hook M.D.
60 months ago
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