[Question #7270] Not sure what to do

5 months ago
Hi , I hope all is well. I have been tracking my CD4 counts for 3 1/2 years and it was always 1000 and it’s gone all the way down to 660 it’s been on the decline And no it’s not a garden virus like you said last time I have been doing this for a long time now and it’s decliningand I still have white tongue which hurts which will not go away . I have been doing a CD4 count every three months and it’s been going down down down and I’m very nervous and I still believe I have HIV is there a test I could do that would be better than the HIVRNAOr the Eliza antibody test. Also I did lose 10 pounds recently and it’s not in my stomach that I lost the weight and both of my arms which is a little weird but I’m really concerned about my CD4 count. Please let me know if there’s another test I could take
Edward W. Hook M.D.
Edward W. Hook M.D.
5 months ago
Welcome back to the Forum.  I’m sorry you continue to worry about HIV despite your negative tests.  As both Dr. Handsfield and I have said before, there are no scientific data which suggest that either acyclovir nor valacyclovir ave a meaningful effect on risk for HIV, nor on the accuracy of tests for HIV infection.  Your tests for HIV have looked for HIV three ways.  The HIV RNA test looks for virus genetic material, the HIV antigen test in the 4th generation tests looks for HIV viral proteins, and the antibody test in the 4th generation test looks for antibodies to HIV made by your body.  If you were infected, all of these tests would be positive.  That none are positive proves that you do not have HIV.  

The CD4 count is a specific test for one sort of lymphocyte and fluctuates substantially.  Routine testing of the sort is not suggested as the counts can be effected by many processes.  My sincere advice is to not worry about HIV, to discuss the results with your own doctor and for a thorough examination.  If he/she feels it is appropriate, seek a referral to a clinical immunologist.  You do not have HIV.

I hope this comment is helpful.  EWH
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