[Question #7450] HIV Test Numbers

4 months ago
Hi doctor,

So in short I had my last test on the 5th of November. The test was done well after the 6 week period recommended by you in the forums. The test came back negative however what peaked my interest is that the result returned with a value of 0.46. In the tests that I have performed in the last 2 years the value has been lower than this.

List of result:
5/11/20 HIV 1&2 ABS+ P24 AG(SERUM) , NEGATIVE, 0.46 
19/7/20 HIV 1&2 ABS+ P24 AG(SERUM) , NEGATIVE, 0.23
31/12/19 HIV 1&2 ABS+ P24 AG(SERUM) , NEGATIVE, 0.19
31/5/19 HIV 1&2 ABS+ P24 AG(SERUM) , NEGATIVE, 0.23
7/3/19 HIV 1&2 ABS+ P24 AG(SERUM) , NEGATIVE, 0.25

Questions:
1. Is the any reason/meaning to the increase in value and what does the value indicate?
2. I have not had any encounter since july nor after the latest test was carried out. Can I take my Nov 5th test as conclusive and move on.
3. In the likely scenario, due to my anxiety over the whole HIV issue, if I do take another HIV test, is there a possibility that i can turn positive,given no known exposure has taken place.

Thank you in advance for your response.
Edward W. Hook M.D.
Edward W. Hook M.D.
4 months ago
Welcome to the Forum.  Thanks for your question. It is a familiar one.  You are overthinking this.  The numerical value is useful to those of us who run laboratories as a means of assuring that our machines are working correctly but are totally irrelevant to interpretation of test results.  The value within the test negative and positive ranges reflect the chemical processes and can vary with things such as room temperature or humidity in the laboratory and well as a long list of other things.  The tests however are engineered in such a way that all negative values are truly negative.  You can have complete faith in your negative test results.  If you months beyond whatever potential exposure that is worrisome, I urge you to believe your test results.  No further testing is needed and additional testing would be a waste of resources.  In answer to your specific questions:

1.  No, the variation is meaningless.
2.  Yes, your results are completely reliable and conclusive 
3.  The is no probability that further testing will find a previously missed infection 

I hope this information is helpful.  I encourage you to move forward.  No further testing is needed.  EWH 
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4 months ago
Hi doctor 

Thank you for the informative response. In regards to exposures, in February of this year I had protected vaginal and unprotected oral which was cleared by the negative result in July. The 2nd was sex toys in august which also was cleared by the negative result in November. 

Is there any anything else to be concerned about?
Edward W. Hook M.D.
Edward W. Hook M.D.
4 months ago
The exposures you describe are very, very low.  There is no realistic reason for concern regarding HIV.  Be confident that you were not infected by either of the exposures you describe.  No need for further testing. EWH ---
4 months ago
Thank you very much Doctor.

You may close the post now.

Stay Safe!
Edward W. Hook M.D.
Edward W. Hook M.D.
4 months ago
thanks for your thanks.  I'm please my comments have been helpful to you.  EWH
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