[Question #7747] Syphillis

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52 months ago
I have had another exsposure.4mths ago
Unprotective oral from csw 
Didnt notice any sores but did develope a itchty rash dr thought it was psoriasis .I still have rge rash nostly arms kegs little worse around the jointsMy hair
has also been recently falling out. Some on head and around eyes
Had a rpr done at weeks but just read on here about rpr being wrong and that Fta abs are better than if + then rpr is done.
Also having back pain n pain in lower leg.
Some vision issues too.
I tried asking the lab if they take steps to peotect aganist prozone but they would not give a clear answer.
Do I need more testing 
How long does rash last if syphilis isnt treated Will it stay come n go ?
Some memory issues but maybe stress ?
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H. Hunter Handsfield, MD
52 months ago
Welcome back to the forum.

You have misread or misunderstood you read about RPR and FTA-ABS. RPR never misses early syphilis (under a year in duration). It's only when late syphilis is suspect and RPR is negative that FTA-ABS ever needs to be done if the RPR is negative, and even this is uncommon. And in fact usually unnecessary, because of IgG testing as well (more about which below). In any case, your symptoms are not very suggestive of syphilis. Syphilis indeed can cause skin rash, but among all types of rash, syphilis is uncommon; and syphilitic rashes rarely itch. And oral sex from a female sex worker is a very low risk exposure for syphilis.

Most labs automatically perform RPR testing in a way that avoids false negative results due to prozone effect -- unless you spoke to a technician who personally does RPR testing, s/he might not have known what you were talking about. However, given your concerns, you could request additional testing. In that event, you should request not an FTA-ABS, but an IgG EIA or ELISA test. These are the normal initial blood tests these days, i.e. before RPR -- unless the doctor or patient specifically requests RPR. So check with the lab on this. If you indeed have had only RPR, have the IgG test. In that event, you can expect a negative result. I suggest this strictly for its reassurance value, not because I suspect you have syphilis. Should it be positive, though, please post a follow-up comment and we'll discuss it further.

Untreated, the skin rash of secondary syphilis lasts anywhere from a week to a few months; it does not come and go. And as noted above, it's itchy.

As we discussed in your previous questions a couple years ago, we don't address or advise about non-STD symptoms, and neither syphilis nor any other STD causes back pain or is a likely cause of "memory issues"

Let me know if anything isn't clear. If you have a syphilis IgG test, I suggest you wait for that result before we go any further into any of this. In the meantime, try not to worry. It is very unlikely you have syphilis or any other STD from the exposure 4 months ago.

HHH, MD
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52 months ago
Sorry I probably read too much in your reply to an earlier question (While it is true that some tests miss syphilis, that applies only to the nontrepoenal tests, i.e. RPR and its cousin, the VDRL test. Indeed, this is one reason the reverse algorithm has been adopted by most labs:  starting with RPR has more potential for missing cases that need further 
I will try n wait to respond till I get suggested test
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H. Hunter Handsfield, MD
52 months ago
Indeed that statement was primarily in relation to late syphilis, not recently acquired infection.---