Hey there, I’m following up on my previous question with some updates/test results. I first noticed clear discharge staining my underwear , and a week later after a long sleep noticed that it was yellow. After that I was tested for trich/gonorreH/chlamydia and those came back negative yesterday. I notice that in my urethra it’s slightly red  starting about 1cm in. 0 dysuria. 0 Meatitis.  I first noticed the staining in my underwear 24-36 hours after receiving oral from a new partner. I had unprotected sex with a different consistent partner about a week prior.  I’ve had these same symptoms before about 6 months ago and was prescribed a Zpack and the symptoms cleared in about 3 days. This time I was given doxy and it has been 3.5 days and I woke up with slight clear discharge again(not enough to leak out but I had that “glued shut” thing. I’m curious why you think it’s taking longer to clear this time. It has me concerned that it’s something viral such as herpes. Is there any possibility of herpes showing up as discharge/painless urethritis being the ONLY symptom? Also is it normal for my symptoms to not be gone by now? Maybe doxy takes slightly longer to clear it than the Zpack did?  Have you seen in your experience bacterial NSU taking longer than a few days to resolve after starting treatment?  Thanks for your services 

Welcome back o the Forum.  I'm sure this is getting frustrating for you.  Several comments and thoughts below, in no particular order:---

Thanks for the reply. I will say this. It’s been 3.5 days since I noticed the yellow staining and I have not noticed any yellow discharge since starting the doxy on that day. I will admit I’m very ocd about this stuff and check quite incessantly. I actually do notice an improvement in the redness inside my urethra today (it was never bad and I was looking closeley) but it is retiring to normal color now, and the clear discharge is lessening it’s just 100% resolved and I guess that’s my qualm. 

Not 100% resolved, that’s my qualm** forgot the word “not” 

Just an update: the redness in urethra is noticeably Imroved. Basically looks normal now. The discharge is a lot less as well, over the 36-48 hours or so I’ve only noticed that “glued shit” (this is a bit of an exaggeration but I’m sure you know what I mean) is only present after a full nights sleep. It doesn’t seem to be enough to stain my underwear like it was.  Before treatment and on days 0-2 after starting doxy I would notice after only a couple of hours of laying down, and underwear would be stained in the morning. My ocd regarding this makes me check it every time wake up in the night tho.  

Thanks for your follow up. At this point you can be 100% sure that you do not have an STI and that unprotected sex with your regular partner does not represent a risk for her. That said, your discharge was not normal. My advice is unchanged with just one small addition.  I still think that evaluation by a urologist may be helpful for you, Looking for another process such as prostatitis or an anatomic variation.  More importantly however I think that your genitally focused anxiety and repeated self examinations are likely to be prolonging your symptoms and contributing to the problem. Work to find a way to keep your hands off of your penis. EWH---

Another update: symptoms appear to be totally resolved , or atleast 95% resolved. It hasn’t even been 5 days since taking the antibiotic, what makes you 100% sure this wasn’t NGU like last time? This timeline fell perfectly within dr handsfields response, and he seemed certain it was ngu. I’m just kind of confused. It’s pretty much totally cleared up why would I need to see a urologist? The doctor I saw a few days ago said this would only be necessary if my symptoms didn’t  get better after a week or so 

You are overly focused on details and nuances.  It may have been NGU but NGU is a CLINICAL SYNDROME which merely describes the finding- in this case urethral inflammation manifest as a urethral discharge.  While far and away most NGU is related to sexual activity but non-STI problems can also cause NGU NGU is also seen with chronic inflammatory problems (rheumatic diseases such a reactive arthritis), as a complication of non-STI viral infections including adenovirus infections and and a long list of other problems.   Urethritis can also occur as the result of anatomic variation (a urological problem) and prostatitis (likewise a urological problem).  Finally, as I've pointed out, repetitive self examination can also cause irritation and resulting discharge.  ---

Thanks for your patience dr hook, I’m sorry for the incessant nature of my questions. The mental side of this is something I’ve battled my whole life and something I’m seeking help for. If the issue recurs again without a new sexual partner I will go to a urologist. I think my expectations were that I’d take a doxy and 24 hours later I’d be 100% back to normal, and when that wasn’t the case my anxiety took over. but I understand the inflammation can take a few days to heal. And I don’t mean to waffle it’s just that there is no pain and there never was.. and the issue seems to be pretty minor that it’s difficult to guAge the healing process. 

Your focus on the discharge is not helping.  To expect complete resolution in 24 hours, particularly with anxiety-fueled repeated self-examination is just not realistic.  ---