[Question #7864] HSV 1 equivocal?
51 months ago
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I got a panel of tests. No symptoms, purely health screening. My HSV 1 IgG test result was equivocal 1.03
What does equivocal mean exactly?
I have no symptoms, never had a cold sore, I do not know of any exposure. I’m in my late 40s and regularly sexually active since 18, more than 25 partners. Should I be concerned about transmitting to others. Are asymptomatic people less likely to transmit? Would I have given it to my partner by now?
What is the treatment, do I need it? Should I retest? (I read that the IgG test misses 30% of hsv cases and therefore isn’t as reliable as the western blot)
51 months ago
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Clarification: i have had just one partner for the past 6 years, so any infection was not recent.
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Terri Warren, RN, Nurse Practitioner
51 months ago
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Equivocal is neither negative nor positive. You tripped something on the test but not fully enough to be considered positive. And if you've had no new partners in the past 6 years and havent' kissed anyone new, it is very unlikely to represent a new infection. If you've never had a cold sore, and it does represent a true positive, then we cannot know if the infection is oral or genital. The best way to sort it out if you really want to know is the herpes western blot. But you already know this, right? You can read about it at westoverheights.com. If I had to take a wild guess, I would suspect perhaps you are not really infected, but the igG test for HSV 1 is not great - it misses 30% of infections so it's very difficult to say. I wouldn't treat anything until you have a symptom that can be swab tested OR you get a positive western blot. And yes, if you are truly infected, which I do doubt, asymptomatic people shed virus less often than people who have outbreaks. As you likely know, about half the adults in the US have HSV 1 infection.
Terri
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