I have just had a routine PCR urine panel (it's a package deal and covers 7 sti's - Gonn, Chlam, MGen, Trich, UU, UP, MH). 

All results negative except UU detected. My ex wife had UU but I never got it and repeatedly tested negative. I'm single so not worried about myself, so much as I am others. 

I tested 5 days after my last unprotected vaginal/brief insertive anal sex exposure (female partner).

For information, I have no symptoms at all. 

Questions:

(1)  do I need to inform previous partners? 

(2) do I need treatment? 

(3) I received brief oral sex without ejaculation last night from a female friend - could she be at risk from me? 

I noted from previous posts that UU doesn't require treatment if no symptoms. However I am simply worried about potentially passing this on to others. Any guidance would be much appreciated. 

Thanks in advance. 

Unprotected sexual exposure was on Tuesday 4th May. 

Tested on Sunday 9th May. 

Results came out today 17th May showing the UU detection.

I reiterate I have no symptoms it was a "peace of mind" test that I did post the event. Will do the HIV and Syph blood work 6 weeks post as well to cover all bases. 

On infrequent occasions, Ureaplasma urealyticum can cause urethritis in men. However, it is an entirely normal bacteria in the genital tract; at any point in time, up to 50% of sexually active persons test positive for it. The large majority of the time, it causes no symptoms or disease of any kind, and in absence of symptoms never requires antibiotic treatment. Most experts, including CDC, recommend that testing for U urealyticum not be offered or included in routine STD testing panels. The American STD Association (ASTDA, of which I am a Board member), soon will be releasing a policy recommendation saying the same. You have no symptoms and your former wife's positive results did not cause her any health problem, nor any problem for you or her (or your) sex partners.

Those comments pretty well cover your numbered questions, but to assure no misunderstanding: 1) There is no need to inform any sex partners about UU; 2) you should not be treated; and 3) UU rarely is found in the mouth or throat; and if present there, not known to cause any health problem.

I hope these comments are helpful and reassuring. Let me know if anything isn't clear.

HHH, MD

Given that today, at 14 days since my unprotected exposure, I have no symptoms and my 5 day-post urine PCR results are negative for all other (more serious) bacterial infections, would it be safe to move on? 

Or should I do any repeat testing just to be sure? If so, at what point in time?

Question re: UU; if UU is detected, and I do not receive treatment, could a follow-up test in a few weeks show negative (ie UU levels will come and go - is that what normally happens)? Does the body clear it alone, etc? 

I completely understand your argument and respect your many years of experience in this field, it's just that getting a positive result for anything can give someone a shock; even though the recommendation today, as you mention, is that UU should not even be included in the standard/routine panel of tests.

Based on the above, what do you suggest I do at this stage?

Many thanks again for your time.

Should you be treated? From a medical standpoint, either for your health or that of current or future sex partners, there is no need. And you need say nothing to partners. However, from a psychological/emotional standpoint -- as well as the concern it could cause if a partner learns about it -- I could understand your desire to do so, and the standard treatment (doxycycline for a week) usually causes no serious side effects or toxicity. But even when UU is treated, it often persists or returns, often because people get reexposed as a normal aspect of human sexuality. Personally, if I were in your situation, I would not be treated. But if you want to consider it, discuss the situation with your doctor. (You could print out this thread as a framework for discussion with her or him.)

Final question from me, can I rely on my negative real-time pcr results for the rest (more serious bacteria) at 5 days post exposure and move on? Also given the absence of symptoms at day 14?

Thanks again and have a great day ahead. 

Thanks again for the thanks. Same to you.