[Question #8163] Follow Up to #7936
48 months ago
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Hi again. Further to my query a few months ago, I had some further questions based on recent events. The previous issue cleared up several days after my last message; however, I have had a recurrence. As last time it seemed to have been a fungal infection, I self-medicated with topical clotrimazole cream for 4-5 days but there was no improvement. Again, there were the raised whitish areas/pimples but this time it actually was worse than the first time. Went back to the urologist who prescribed me a combined anti-fungal/bacterial/steroid cream pending lab results, as well as oral flucozonale (2 doses, 1 week apart). (The swabs this time were negative for bacteria/fungal but I was using topical clotrimazole cream at that point so the Urologist said this is not definitive). The whitish sores/pimples have receded but there remains a lot of inflammation/soreness/slow healing even after 8 days, so the urologist advised to see a dermatologist. Dermatologist advised me to stop taking the ointment as 8 days should have been enough if it was fungal, but that she still suspects herpes even after the negative HSV2 blood test in June as if it was fungal it should have cleared by now and the positive candida result in June may have been secondary/coincidental. She has taken a PCR swab and also given me an HSV1 blood test - results pending; however, she said that as I've been using the topical cream the PCR swab may not be 100% accurate. Again, with my sexual history this is all rather strange to me, however, she is saying I could have acquired HSV1 genitally from my wife in the course of oral sex. Anyway, I am now using a new herpes focused topical treatment as she has prescribed.
I would be curious to get your opinion based on the history and previous events. To be honest I thought I already had HSV1 from childhood/adolescence, although I don't think I have ever had a cold sore in my life. How likely is this to be Herpes based on your experience? Is there anything I can do to vali
48 months ago
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I would be curious to get your opinion based on the history and previous events. To be honest I thought I already had HSV1 from childhood/adolescence, although I don't think I have ever had a cold sore in my life. How likely is this to be Herpes based on your experience? Is there anything I can do to validate this as to be honest I've been left rather confused (and sore) from this experience. Can candidal balanitis get confused with herpes? If it is HSV1, what is the prognosis/treatment and best way forward? Would a PCR test be effective at this point given there are no active lesions, only redness/inflammation?
48 months ago
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Sorry, one other comment. Another reasons I'm not sure about a possible herpes diagnosis as that at no point has there been any scabbing, which I though was typical of herpatic sores? Again, not sure if that is correct or not.
48 months ago
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Quick update: the STD 10 Panel Real Time PCR was negative for all items tested, including HSV1 and HSV2. I don't know how reliable this is. I still have redness/tenderness around the entire area, although it seems to be very slowly healing.
I also looked online and apparently the initial topical treatment I was prescribed has side effects that can include: skin irritation, redness, thinning of skin. I am now wondering if I am now suffering more as a result of the treatment side effects but to be honest am just feeling rather fed up and confused by the entire episode.
Sorry for all the information / questions, but having now seen two different doctors am trying to make sense of the situation.
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Terri Warren, RN, Nurse Practitioner
48 months ago
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Chris, I'll be right back to answer your questions.
Terri
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Terri Warren, RN, Nurse Practitioner
48 months ago
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This is indeed puzzling. The IgG test is simply not very reliable, particularly for HSV 1. It misses 30% of HSV 1 infections, compared to the western blot, so I would not rely upon this result.
Given all this confusion,I would strongly recommend that you get a herpes western blot for greatest clarity. I'm worried that what you had applied topically could have influenced the PCR swab or that it was done too late for accuracy. This test is only done at the University of Washington but I can order it for you at westoverheights.com or you can work with your own provider to get this done. I'm going to leave this open for a bit to conclude this discussion, OK?
Terri
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48 months ago
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Hi. Thanks for the response. I am not based on North America so unfortunately not sure if the Western Blot will be an option.
Apparently the HSV1 blood test was negative, but as you say, it's not 100% reliable.
The anti-viral cream I have been using for 3 days does not seem to be helping either so the Doctor has advised to stop that for now.
I'm going for another check up this morning. I am wondering if it was a yeast infection after all that was not responding well to the clotrimazole, but that the steroid cream applied afterwards created additional issues. Or possibly an allergy to something in the topical creams/ointments is complicating matters?
I am hoping to find a resolution to all this soon.
Would Herpes normally cause generalised redness/irritation around the entire foreskin / area below the glans? Or is it normally more localised? Basically I now have redness/inflammation around the entire area (not so much the glans but foreskin / below glans). No scabbing at all.
Is there any clear way to differentiate clinically between candidal balanitis and Herpes?
48 months ago
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HSV1 Blood Test Results
HSV 1 IGM ABS EIA 0.1
HSV 1 IGG ABS EIA 0.1
48 months ago
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So I saw another Dermatologist today as a follow up who acknowledged it was a challenging case. He says Candida can be ruled out given the oral flucozonale and topical anti-fungals used. He is sceptical of Herpes as he said it was more generalised redness/soreness verses specific localised sores, especially given the blood tests and that it hadn't seemed to respond the topical treatment over 3 days. He also said that my lymph nodes around the groin were normal (not swollen). He said Zoon's Balinitis was another possibility but that my age makes that unlikely and also that Zoon's would have responded to the steroid cream used for several days. He noticed some weeping/discharge/wetness in the affected area under the foreskin below the glans and he suspects a bacterial infection of some kind that did not show up on the earlier tests. He has put me on doxycycline for 2 weeks and advised to stop all topical application except a non-medicated moisturising/nappy rash sort of cream to help the area heal and to monitor over the next several days. He also gave me another urine test and is reperforming the swabs/PCR tests. He mentioned Chlamidya at one point but again that doesn't make sense given my sexual history.
I'm not sure if there is any advice you can give on all this. I know it's not normal procedure, but given now that a bacterial infection is being discussed, I'm not sure if Dr. Hook or Dr. Handsfield would have any comments to add on all this based on their experience. I appreciate that there is a lot of information in this and the earlier query but having now seen a urologist and two dermatologists over the last 2 weeks I remain somewhat in the dark. Please let me know if any advice or questions that can help clarify matters.
48 months ago
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One other quick addition. Now that I have stopped using the different topical applications, it seems to be evident that there is some sticky yellow discharge around the area. I am not sure if it is from the urethra or the inflamed area under the foreskin. Would this support the diagnosis of a beacterial infection of some kind?
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Terri Warren, RN, Nurse Practitioner
48 months ago
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Herpes would not cause generalized redness, no, it causes specific sore. Candida causes generalized redness and is common in men who still have a foreskin, yes. But apparently the doctor doesn't think that this is the case. Were bacterial cultures taken from the affected area? I assume that they were taken as a decision on an antibiotic was made based on something.
You are well past the allowed number of posts here. If you would like to get an opinion from Dr. Hook or Handsfield, please feel free to start a new post under the STI heading. Glad to hear your HSV 1 IgG is negative.
Terri
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