[Question #8188] Follow-up to Question #8095

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47 months ago
Hi Dr Handsfield. I just have a follow-up to Question #8095 based on the last response you provided.
To recap - I had penile discharge after extremely low risk exposure. Tested negative for gonorrhea and chlamydia but was treated with Azithromycin (4 tabs), ceftriaxone injection & 7 days of cipro as a precaution. You recommended retesting (expecting negative results) post 6 weeks, as a matter of standard practice, on the assumption it was NGU. I asked about other STDs and you mentioned Mycoplasma Genitalium and on the last post mentioned it would be rarely (if ever) transmitted by hand-genital contact. I had follow-up testing (HIV, Syphilis, HepC, HPV, HSV,  Heb B,  Trich, gonorrhea &chlamydia) and added MG as part of this.  All came back negative as you expected. However I have a couple of follow-up questions:
- If it was originally MG or Trich  - would I have still tested positive at this second round of testing or would the treatment noted above have cleared it? I understand the treatment regimen for these two STDs is different from what I was given.
- Alternatively - could I have self cleared MG or Trich within this timeframe?
I would just like to rule out any possibility of transmission to my regular partner based on the mutual masturbation described in my previous post where you said there was no need to inform her of all this testing. I have read that MG can be transmitted even without penetration, hence this clarification request.
Thanks for your help.

 
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H. Hunter Handsfield, MD
47 months ago
Thanks for the follow-up questions and comments.

Both trichomonas and M genitalium were unlikely on statistical grounds:  MG causes ~15% of NGU and trich ~5%. Azithromycin cures M. genitalium about half the time, and ciprofloxacin has some activity and may or may not be effective. At this point there is no way to know whether you never had it (which is likely) or had it and were cured. However, you can be sure you didn't have trich, which would not have been affected by the antibiotics you received.

I am unaware of any credible reports of M. genitalium transmitted without penetration. There is a lot of misinformation about MG on various nonprofessional sites. I would ignore whatever you read about hand-genital transmission. That said, this entire situation is atypical, with apparently well documented NGU despite an exceedingly low risk exposure. But at this point I would advise you to move on with no further worries about any of this.

Let me know if anything isn't clear. Best wishes and stay safe--

HHH, MD
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